Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0054119937
Study information
Scientific title
Acronym
Study hypothesis
Which of the currently available methods (entonox, intravenous morphine, subcutaneous bupivacaine) used for the control of analgesia during chest drain removal is most effective?
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Signs and Symptoms: Pain
Intervention
Patients randomised to 50% entonox, 100 mcg/kg morphine and 0.5% bupivacaine.
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
1. Pain scores after chest drain removal assessed by the short form McGill questionnaire 2. Effect of anaesthetic agent on length of intensive care unit stay
Secondary outcome measures
Not provided at time of registration
Overall trial start date
15/07/2002
Overall trial end date
15/07/2003
Reason abandoned
Eligibility
Participant inclusion criteria
66 patients receiving chest drain removal following major cardiac surgery.
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
66
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
15/07/2002
Recruitment end date
15/07/2003
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Department of Anaesthesia
Liverpool
L14 3PE
United Kingdom
Sponsor information
Organisation
Department of Health (UK)
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
The Cardiothoracic Centre Liverpool NHS Trust (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
2005 results in http://www.ncbi.nlm.nih.gov/pubmed/15616079
Publication citations
-
Results
Akrofi M, Miller S, Colfar S, Corry PR, Fabri BM, Pullan MD, Russell GN, Fox MA, A randomized comparison of three methods of analgesia for chest drain removal in postcardiac surgical patients., Anesth. Analg., 2005, 100, 1, 205-209, doi: 10.1213/01.ANE.0000140237.96510.E5.