Condition category
Signs and Symptoms
Date applied
12/09/2003
Date assigned
12/09/2003
Last edited
17/12/2008
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr M Akrofi

ORCID ID

Contact details

Department of Anaesthesia
The Cardiothoracic Centre
Liverpool NHS Trust
Thomas Drive
Liverpool
L14 3PE
United Kingdom
+44 (0)151 228 1616

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0054119937

Study information

Scientific title

Acronym

Study hypothesis

Which of the currently available methods (entonox, intravenous morphine, subcutaneous bupivacaine) used for the control of analgesia during chest drain removal is most effective?

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Signs and Symptoms: Pain

Intervention

Patients randomised to 50% entonox, 100 mcg/kg morphine and 0.5% bupivacaine.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

1. Pain scores after chest drain removal assessed by the short form McGill questionnaire 2. Effect of anaesthetic agent on length of intensive care unit stay

Secondary outcome measures

Not provided at time of registration

Overall trial start date

15/07/2002

Overall trial end date

15/07/2003

Reason abandoned

Eligibility

Participant inclusion criteria

66 patients receiving chest drain removal following major cardiac surgery.

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

66

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

15/07/2002

Recruitment end date

15/07/2003

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Department of Anaesthesia
Liverpool
L14 3PE
United Kingdom

Sponsor information

Organisation

Department of Health (UK)

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Sponsor type

Government

Website

http://www.doh.gov.uk

Funders

Funder type

Government

Funder name

The Cardiothoracic Centre Liverpool NHS Trust (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2005 results in http://www.ncbi.nlm.nih.gov/pubmed/15616079

Publication citations

  1. Results

    Akrofi M, Miller S, Colfar S, Corry PR, Fabri BM, Pullan MD, Russell GN, Fox MA, A randomized comparison of three methods of analgesia for chest drain removal in postcardiac surgical patients., Anesth. Analg., 2005, 100, 1, 205-209, doi: 10.1213/01.ANE.0000140237.96510.E5.

Additional files

Editorial Notes