Contact information
Type
Scientific
Primary contact
Dr Iain Murray
ORCID ID
Contact details
Royal Cornwall Hospitals NHS Trust
Treliske
Truro
TR1 3LJ
United Kingdom
+44
Iain.Murray@rcht.cornwall.nhs.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0202140085
Study information
Scientific title
Acronym
Study hypothesis
How many patients develop MRSA infection to their gastrostomy site using our present antibiotic prophylaxis and whether infection can be prevented by the use of intravenous teicoplanin or by inserting the gastrostomy tube radiologically rather than endoscopically?
Ethics approval
Not provided at time of registration
Study design
Prospective randomised pilot study
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Condition
Signs and Symptoms: MRSA peristomal infections
Intervention
Use of intravenous teicoplanin or inserting the gastrostomy tube radiologically rather than endoscopically.
Added May 2008: Randomised:
1. RIG + cefotaxime
2. PEG + cefotaxime
3. PEG + teicoplanin
Intervention type
Drug
Phase
Not Specified
Drug names
teicoplanin
Primary outcome measures
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/06/2004
Overall trial end date
31/12/2006
Reason abandoned
Interim results no reduction in MRSA infection rate provided either by use of teicoplanin or with the tube being inserted radiologically rather than endoscopically.
Eligibility
Participant inclusion criteria
Added May 2008:
1. Subjects over 16 years
2. Referred for PEG/RIG
3. Informed written consent
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
Planned 240
Participant exclusion criteria
Added May 2008:
1. Oropharyngeal cancer
2. Already taking antibiotics
Recruitment start date
01/06/2004
Recruitment end date
31/12/2006
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Royal Cornwall Hospitals NHS Trust
Truro
TR1 3LJ
United Kingdom
Sponsor information
Organisation
Department of Health
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
+44 (0)20 7307 2622
dhmail@doh.gsi.org.uk
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
Royal Cornwall Hospitals NHS Trust (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary