Condition category
Skin and Connective Tissue Diseases
Date applied
12/05/2010
Date assigned
12/05/2010
Last edited
05/02/2016
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Sophie Weatherhead

ORCID ID

Contact details

Newcastle University
Dermatology
2nd Floor William Leech Building
Medical School
Newcastle
NE2 4HH
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

6639

Study information

Scientific title

Role of epidermal apoptosis in the clearance of psoriatic plaques: a single centre non-randomised trial

Acronym

MECH-PSOR-CLEAR

Study hypothesis

To investigate whether anti-psoriatic treatments induce epidermal apoptosis, and whether this may account for plaque clearance.

Ethics approval

MREC approved (ref: 2002/255)

Study design

Single centre non-randomised trial

Primary study design

Observational

Secondary study design

Single-centre

Trial setting

Other

Trial type

Treatment

Patient information sheet

Not available in web format, please use contact details to request a participant information sheet

Condition

Topic: Skin; Subtopic: Skin (all Subtopics); Disease: Dermatology

Intervention

Biopsies (skin).

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Apoptotic epidermal cells

Secondary outcome measures

Effect of gender, age and treatment

Overall trial start date

01/09/2002

Overall trial end date

30/04/2013

Reason abandoned

Eligibility

Participant inclusion criteria

Not provided at time of registration

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

Planned sample size: 100

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

01/09/2002

Recruitment end date

30/04/2013

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Newcastle University
Newcastle
NE2 4HH
United Kingdom

Sponsor information

Organisation

Newcastle upon Tyne Hospitals NHS Foundation Trust

Sponsor details

Royal Victoria Infirmary
Queen Victoria Road
Newcastle Upon Tyne
NE1 4LP
United Kingdom

Sponsor type

Government

Website

http://www.newcastle-hospitals.org.uk/services/index.aspx

Funders

Funder type

Charity

Funder name

Psoriasis Association (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes

05/02/2016: No publications found, verifying study status with principal investigator