Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
6639
Study information
Scientific title
Role of epidermal apoptosis in the clearance of psoriatic plaques: a single centre non-randomised trial
Acronym
MECH-PSOR-CLEAR
Study hypothesis
To investigate whether anti-psoriatic treatments induce epidermal apoptosis, and whether this may account for plaque clearance.
Ethics approval
MREC approved (ref: 2002/255)
Study design
Single centre non-randomised trial
Primary study design
Observational
Secondary study design
Single-centre
Trial setting
Other
Trial type
Treatment
Patient information sheet
Not available in web format, please use contact details to request a participant information sheet
Condition
Topic: Skin; Subtopic: Skin (all Subtopics); Disease: Dermatology
Intervention
Biopsies (skin).
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measure
Apoptotic epidermal cells
Secondary outcome measures
Effect of gender, age and treatment
Overall trial start date
01/09/2002
Overall trial end date
30/04/2013
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Not provided at time of registration
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
Planned sample size: 100
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/09/2002
Recruitment end date
30/04/2013
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Newcastle University
Newcastle
NE2 4HH
United Kingdom
Sponsor information
Organisation
Newcastle upon Tyne Hospitals NHS Foundation Trust
Sponsor details
Royal Victoria Infirmary
Queen Victoria Road
Newcastle Upon Tyne
NE1 4LP
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Charity
Funder name
Psoriasis Association (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list