The effect of cataract surgical techniques on the corneal endothelium: a comparison between conventional phacoemulsification with Aqualase

ISRCTN	ISRCTN41218609
DOI	https://doi.org/10.1186/ISRCTN41218609
Secondary identifying numbers	N0141187713

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Mr Scott Hau
Scientific

Moorfields Eye Hospital
162 City Road
London
EC1V 2PD
United Kingdom

Phone	+44
Email	Scott.Hau@moorfields.nhs.uk

Study design	Randomised controlled pilot study
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Treatment
Scientific title
Study objectives	To compare two techniques of cataract surgery: conventional phacoemulsification versus the newer Aqualase technique especially looking at the rate of corneal endothelial cell loss and complications rate seen with each technique.
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Eye Diseases: Cataract
Intervention	1. Standard phacoemulsification 2. Aqualase
Intervention type	Other
Primary outcome measure	Percentage of cell loss
Secondary outcome measures	1. Coefficient of variation and hexagonality of cell sizes at 3 months 2. Per-and-postoperative complications
Overall study start date	20/09/2006
Completion date	20/12/2006

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target number of participants	30 patients - 30 eyes in each group
Key inclusion criteria	Routine cataracts less than or equal to grade 3 determined by Oxford grading scale
Key exclusion criteria	1. Other ocular or systemic co-morbidity factors 2. Patients with an axial length greater than 26.5mm 3. Combined procedures 4. Cataracts greater than grade 3
Date of first enrolment	20/09/2006
Date of final enrolment	20/12/2006

Moorfields Eye Hospital

London
EC1V 2PD
United Kingdom

Record Provided by the NHSTCT Register - 2007 Update - Department of Health
Government

The Department of Health, Richmond House, 79 Whitehall
London
SW1A 2NL
United Kingdom

Government

Moorfields Eye Hospital NHS Foundation Trust (UK) NHS R&D Support Funding

No information available

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan