Insecticide Treated bedNets (ITNs) for malaria control in Urban Accra
| ISRCTN | ISRCTN42261314 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN42261314 |
| Secondary identifying numbers | N/A |
- Submission date
- 31/01/2008
- Registration date
- 04/04/2008
- Last edited
- 04/06/2019
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Infections and Infestations
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Martin Donnelly
Scientific
Scientific
Liverpool School of Tropical Medicine
Pembroke Place
Liverpool
L35QA
United Kingdom
Study information
| Study design | Non-randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Non randomised controlled trial |
| Study setting(s) | Other |
| Study type | Prevention |
| Scientific title | Insecticide Treated bedNets (ITNs) for malaria control in Urban Accra |
| Study objectives | The main objectives of the study: 1. Assess if bednets can be used as rapid, high coverage control method for malaria in urban areas 2. Investigate the effect of ITN introduction on malaria, anaemia and anthropometric measurements 3. Assess the use of haemoglobin level as a measurement of intervention efficacy by controlling for nutritional and geohelminth confounding factors |
| Ethics approval(s) | 1. Liverpool School of Tropical Medicine, UK, approved on 23 September 2002 (ref: 02:50). Some amendments to the existing clearance were reviewed on the 30 April 2004 with additional approval granted on 3rd June 2004. 2. Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, ethical clearance granted in September 2002 |
| Health condition(s) or problem(s) studied | Malaria and anaemia |
| Intervention | Insecticide treated bednets vs no intervention (Control group received bednets after six months) It was not possible to randomly allocate children to the two arms of the study as the intervention was community based. The insecticide treated nets were distributed in the intervention community and therefore all children surveyed in that community entered the intervention arm. All households with children under 10 and/or pregnant women in the control community received an insecticide treated nets after six months. Duration of intervention: 6 months (although the insecticide treated nets remained the property of the study subjects) |
| Intervention type | Other |
| Primary outcome measure | The following were assessed at enrolment, 3 and 6 months: 1. Moderate anaemia, provisionally defined as a haemoglobin level <9 g/dl 2. Haemoglobin level as a continuous variable (in g/dl) 3. Density of infection defined as parasitaemia >5,000 parasites/mm3 |
| Secondary outcome measures | No secondary outcome measures |
| Overall study start date | 20/05/2004 |
| Completion date | 17/12/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Child |
| Lower age limit | 1 Month |
| Upper age limit | 10 Years |
| Sex | Both |
| Target number of participants | 600 |
| Total final enrolment | 498 |
| Key inclusion criteria | Children aged over 1 month and under 10 years |
| Key exclusion criteria | Children with haemoglobin (Hb) <8g/dl who will require iron supplementation |
| Date of first enrolment | 20/05/2004 |
| Date of final enrolment | 17/12/2004 |
Locations
Countries of recruitment
- England
- Ghana
- United Kingdom
Study participating centre
Liverpool School of Tropical Medicine
Liverpool
L35QA
United Kingdom
L35QA
United Kingdom
Sponsor information
Liverpool School of Tropical Medicine (UK)
University/education
University/education
c/o Dr Martin Donnelly
Pembroke Place
Liverpool
L35QA
England
United Kingdom
| Website | http://www.liv.ac.uk/lstm/ |
|---|---|
"ROR" |
https://ror.org/03svjbs84 |
Funders
Funder type
Government
The Department for International Development (DfID) Malaria Knowledge Programme of the Liverpool School of Tropical Medicine (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/07/2010 | 04/06/2019 | Yes | No |
Editorial Notes
04/06/2019: Total final enrolment and publication reference were added.
