Condition category
Not Applicable
Date applied
Date assigned
Last edited
Retrospectively registered
Overall trial status
Recruitment status
No longer recruiting

Plain English Summary

Background and study aims
The aim of this study is to assess the effectiveness of reminders in patients’ electronic medical records, to find out whether they improve control of chronic (long-term) diseases such as diabetes, high blood pressure and heart disease, and encourage preventive activity, such as influenza vaccination and smoking cessation.

Who can participate?
Family doctors and nurses of the primary care teams of the Catalan Health Institute

What does the study involve?
Participating primary care teams are randomly allocated into four groups. Three of the groups receive three different types of reminders in their patients’ medical records: either pop-up reminders, pop-up reminders and calendar icons, or pop-up reminders, calendar icons and configurability (users can select how the reminders are shown). The fourth group do not receive reminders.

What are the possible benefits and risks of participating?
The main benefit is to provide information targeted to improve patient care when they are visiting, regardless of the reason for the consultation. The risks are minor and are related to some stress for the availability of clinical information unrelated to the reason for patient consultation. This effect is however unimportant, considering that the information is relevant to the health of the patient.

Where is the study run from?
Catalan Health Institute (Spain)

When is the study starting and how long is it expected to run for?
February 2012 to January 2013

Who is funding the study?
Investigator initiated and funded

Who is the main contact?
Dr Manuel Medina Peralta

Trial website

Contact information



Primary contact

Dr Manuel Medina Peralta


Contact details

Gran Via de les Corts Catalanes

Additional identifiers

EudraCT number number

Protocol/serial number


Study information

Scientific title

Randomized clinical trial to evaluate the effectiveness of synchronous electronic clinical reminders for professionals of primary care


Study hypothesis

Main hypothesis:
To provide synchronous electronic clinical reminders in patient records with a clinical situation to be improved, detection of a chronic disease or prevention activity. The electronic clinical reminders improves the clinical practice of professionals by reducing the number of clinical conditions likely to recall and improving its resolution.

Secondary hypothesis:
1. To add trademarks on the agenda of professionals to help prioritize those patients with a greater number of clinical situations which will further contribute to improving clinical practice.
2. To allow the auto-configurability of reminder system and trademarks on the agenda which will further contribute to improving clinical practice.

Ethics approval

Ethics Committee on Clinical Research of the Primary Care Research Institute (IDIAP) Jordi Gol. Barcelona, 25/11/2011, ref: P11/62

Study design

Non-blinded randomized controlled trial

Primary study design


Secondary study design

Randomised controlled trial

Trial setting

GP practices

Trial type


Patient information sheet

Not available in web format, please use the contact details to request a participant information sheet


Clinical reminders for chronic diseases in primary care


The 270 primary care teams are divided randomly into four groups adjusted by their previous results in a quality of care synthetic indicator (consists of 62 clinical sub-indicators)

The control group consists of professional from 135 teams don’t receive intervention.

Professionals from the other three groups receive reminders in the computerized medical record, based on recommendations from clinical practice guidelines and linked to the patient. Reminder status is updated weekly for the duration of the intervention depending on the study subgroup in one of the following:

Subgroup 1: "Reminder in record": Professionals see reminders synchronously with the patient visit and they can directly access the module where the situation is resolved.

Subgroup 2: “mark on the agenda”: In addition to the intervention of subgroup 1, the professionals see a mark on the agenda by identifying those patients with reminders and the number of these, allowing a greater prioritization of patients to address.

Subgroup 3: “auto-configure”: In addition to the intervention of subgroup 2, professionals can configure reminders, focusing on those that most interest them, to keep in mind.

Intervention type



Not Applicable

Drug names

Primary outcome measures

1. Resolved reminder
2. Time from onset to resolution reminder

Secondary outcome measures

1. Type of clinical situation that generates the reminder
2. Type of reminder
3. Characteristics of the team:
3.1. Socioeconomic level of population
3.2. Dispersion level of population alloted
3.3. Existence of post-graduate teaching in family medicine
3.4. Existence of undergraduate nursing teaching
4. Characteristics of professionals
4.1. Type of professional: physician or nurse
4.2. Age
4.3. Sex
4.4. Type of contract

Overall trial start date


Overall trial end date


Reason abandoned


Participant inclusion criteria

3,425 family physicians and 3,262 nurses caring for adult population of the 279 Primary Care Teams (PCT) managed by the Catalonian Health Institute.

Participant type

Health professional

Age group




Target number of participants

3425 general practitioners and 3262 primary care nurses

Participant exclusion criteria

1. Professionals from seven primary care teams involved in another clinical trial related to the emergence of brands in the professional agenda
2. Professionals from two primary care teams that were in a process of reorganization to become four different teams, which made the process of randomization difficult
3. 150 professionals who have a much lower attendance schedule and a very low computerization of their consultations

Recruitment start date


Recruitment end date



Countries of recruitment


Trial participating centre

Gran Via de les Corts Catalanes, 587-589

Sponsor information


Primary Care Research Institute (IDIAP) Jordi Gol (Spain)

Sponsor details

Gran Via de les Corts Catalanes

Sponsor type

Hospital/treatment centre



Funder type


Funder name

Investigator initiated and funded (Spain)

Alternative name(s)

Funding Body Type

Funding Body Subtype


Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2016 protocol in:

Publication citations

Additional files

Editorial Notes

14/02/2017: Plain English summary added. 22/09/2016: Publication reference added.