A randomised controlled trial of cognitive therapy for command hallucinations
| ISRCTN | ISRCTN42620357 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN42620357 |
| Secondary identifying numbers | RGC00391 |
- Submission date
- 23/01/2004
- Registration date
- 23/01/2004
- Last edited
- 29/01/2010
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Peter Trower
Scientific
Scientific
University of Birmingham / South Bham Mental Health Trust
Queen Elizabeth Psychiatric Hospital
Mindelsohn Way
Birmingham
B15 2TT
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | |
| Study objectives | The objective is to evaluate whether a form of cognitive therapy (CT) developed by the applicants is an effective form of treatment for command hallucinations. The researcher's cognitive model asserts that high risk behaviours of command hallucinators are a consequence of core beliefs, namely a conviction in the power of their voices and a belief that they are compelled to comply with and appease these voices. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Schizophrenia and other psychoses |
| Intervention | 1. Cognitive therapy 2. Control |
| Intervention type | Other |
| Primary outcome measure | 1. Voices: 1.1. Content - Cognitive Assessment Schedule (Chadwick & Birchwood, 1995) 1.2. Topograph - Frequency, volume, audibility, affect (Hustig & Hafner, 1992) 1.3. Beliefs and evidence 1.3.1. Beliefs About Voices Questionnaire (Chadwick & Birchwood, 1995) 1.3.2. Maudsley Assessment of Delusions Schedule (Buchanan et al 1993) 1.4. Compliance (Beck-Sander et al 1997) 2. Affect: 2.1. Depression, hopelessness (Calgary Depression Scale for Schizophrenia: Addington & Addington, 1993) 3. Mental State: 3.1. Positive and Negative Syndrome Scale (PANSS) (Kay, 1997) 3.2. Previous episodes of 'risk' behaviours |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/10/1999 |
| Completion date | 01/10/2001 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | 52 |
| Key inclusion criteria | The sample will be drawn from the case registers of patients receiving treatment from South and North Birmingham Mental Health Trusts. From this sample base the researchers will draw a cohort of patients conforming to International Statistical Classification of Diseases and Related Health Problems, Tenth revision (ICD-10) schizophrenia who have experienced auditory command hallucinations for a minimum of six months. There will 26 patients in each of the groups. |
| Key exclusion criteria | 1. Current drug and alcohol misuses 2. Primary organic disorder This is to ensure that the auditory hallucinations are a symptom of schizophrenia rather than induced by drugs or the result of organic impairment. |
| Date of first enrolment | 01/10/1999 |
| Date of final enrolment | 01/10/2001 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
University of Birmingham / South Bham Mental Health Trust
Birmingham
B15 2TT
United Kingdom
B15 2TT
United Kingdom
Sponsor information
NHS R&D Regional Programme Register - Department of Health (UK)
Government
Government
The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Phone | +44 (0)20 7307 2622 |
|---|---|
| dhmail@doh.gsi.org.uk | |
| Website | http://www.doh.gov.uk |
Funders
Funder type
Government
NHS Executive West Midlands (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/04/2004 | Yes | No |
