Comparison of blood loss following the use of chlorhexidine acetate to saline for lavage during primary total knee replacement
| ISRCTN | ISRCTN42907199 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN42907199 |
| Secondary identifying numbers | N0202133839 |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 17/04/2015
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr M Divekar
Scientific
Scientific
Royal Cornwall Hospitals NHS Trust
Treliske
Truro
TR1 3LJ
United Kingdom
| Phone | +44 (0)1872 253960 |
|---|---|
| abc@email.com |
Study information
| Study design | Double-blind randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | Comparison of blood loss following the use of chlorhexidine acetate to saline for lavage during primary total knee replacement |
| Study objectives | Is there an increase (statistically significant) in blood loss following use of chlorhexidine acetate to lavage the knee in total knee replacement? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Surgery: Knee arthroplasty |
| Intervention | 130 volunteers will have saline or chlorhexidine acetate used to lavage and blood loss estimated at 48 hours. |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | Chlorhexidine acetate |
| Primary outcome measure | Excess of 50 ml blood loss in chlorhexidine acetate group will be considered significant. |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/07/2003 |
| Completion date | 31/03/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | 130 |
| Key inclusion criteria | 130 patients |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/07/2003 |
| Date of final enrolment | 31/03/2006 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Royal Cornwall Hospitals NHS Trust
Truro
TR1 3LJ
United Kingdom
TR1 3LJ
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.dh.gov.uk/Home/fs/en |
|---|
Funders
Funder type
Government
Royal Cornwall Hospitals NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
