An evaluation of a brief assessment-led intervention with young non-injecting drug users

ISRCTN	ISRCTN43192662
DOI	https://doi.org/10.1186/ISRCTN43192662
Secondary identifying numbers	V#1, 10/01/06

Submission date: 13/02/2008
Registration date: 26/02/2008
Last edited: 06/08/2020

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Mental and Behavioural Disorders

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr John Marsden
Scientific

Institute of Psychiatry
King's College London
PO Box 048
4 Windsor Walk
London
SE5 8AF
United Kingdom

Email	J.Marsden@iop.kcl.ac.uk

Study information

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Not specified
Study type	Prevention
Participant information sheet	Not available in web format, please use the contact details to request a patient information sheet
Scientific title	An evaluation of a brief assessment-led intervention with young non-injecting drug users
Study objectives	That participants receiving a brief assessment-led intervention would at 3 months follow-up have a lower mean frequency of cannabis use, cocaine use, crack cocaine use and MDMA (3,4 methylenedioxymethamphetamine; Ecstasy) use combined than delayed assessment control participants
Ethics approval(s)	King's College London, 17/10/2005, ref: 05/Q0706/219
Health condition(s) or problem(s) studied	Substance misuse
Intervention	Experimental: A brief assessment-led intervention a. Drugs and Lifestyle Assessment b. Manual guided 30 minute feedback interview Control 1: Assessment only Control 2: Delayed assessment
Intervention type	Behavioural
Primary outcome measure	Combined frequency of cocaine powder use, crack cocaine use, MDMA use and cannabis use, assessed at baseline and 90 days
Secondary outcome measures	The following were assessed at baseline and 90 days: 1. Typical intensity of cannabis use, cocaine use, crack cocaine use and MDMA use at 90 days 2. Drug dependency: Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) Personality Disorders (Structured Clinical Interview for DSM-IV Axis II Personality Disorders; SCID-II) 3. Alcohol frequency and intensity 4. Hazardous drinking: The Alcohol Use Disorders Identification Test (AUDIT) 5. General health: EQ-5D A multi-dimensional Quality of Health Instrument (EurQol) 6. Psychological health: General Health Questionnaire (GHQ 12) 7. Engagement with health and social services
Overall study start date	01/10/2005
Completion date	29/01/2008

Eligibility

Participant type(s)	Other
Age group	Adult
Sex	Both
Target number of participants	255
Total final enrolment	342
Key inclusion criteria	1. 16 to 28 years old 2. Using either cannabis, cocaine powder, crack cocaine, or MDMA on four days in previous month 3. Able speak and comprehend English 4. Written consent
Key exclusion criteria	1. In contact with a drug/alcohol treatment agency in previous 12 months 2. Used opiates more than 30 days in the previous 90 days or in the previous 48 hours before interview 3. Injected more than once in the last 12 months and no more than ten times lifetime 4. Receiving specialist treatment for a mental health problem 5. Participated in a similar research study in the previous 12 months
Date of first enrolment	01/10/2005
Date of final enrolment	29/01/2008

Locations

Countries of recruitment

England
United Kingdom

Study participating centre

Institute of Psychiatry

London
SE5 8AF
United Kingdom

Sponsor information

King's College London (UK)
University/education

Institute of Psychiatry
Kings College London
4 Windsor Walk
London
SE5 8AF
England
United Kingdom

Email	gill.lambert@iop.kcl.ac.uk
Website	http://www.iop.kcl.ac.uk
"ROR"	https://ror.org/0220mzb33

Funders

Funder type

Government

Department of Health of England & Wales, Drug Misuse Research Initiative (Phase 2) (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/07/2006	06/08/2020	Yes	No

Editorial Notes

06/08/2020: The following changes were made to the trial record:
1. Publication reference added.
2. The total final enrolment was added.
08/06/2017: No publications found, verifying study status with principal investigator.