Does giving advice on avoiding allergies and triggers improve asthma control? A research trial

ISRCTN	ISRCTN45684820
DOI	https://doi.org/10.1186/ISRCTN45684820
Secondary identifying numbers	04/016

Submission date: 13/02/2008
Registration date: 26/02/2008
Last edited: 21/06/2010

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Respiratory

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof Chris Griffiths
Scientific

Centre for Health Sciences
Barts and the London Medical School
2 Newark st
London
E1 4NS
United Kingdom

Study information

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Not specified
Study type	Quality of life
Scientific title	Does structured advice on Allergy and Allergen Avoidance given by practice nurses improve control of asthma in primary care? A single blind randomised controlled trial
Study acronym	AAA
Study objectives	The control of asthma can be improved by a structured allergy assessment followed by individualised avoidance advice, given by practice nurses in primary care.
Ethics approval(s)	Ethics approval received from Bristol South NHS Ethics Committee on the 15th November 2004.
Health condition(s) or problem(s) studied	Asthma
Intervention	Control patients: Usual care asthma reviews (UC) consisted of assessment of symptoms, inhaler technique, and medication usage, and provision of self-management action plans. Intervention patients: Structured allergen and trigger avoidance advice reviews (AAA) comprised the elements of a usual review as above, supplemented by a structured asthma and allergy assessment consisting of: 1. Skin prick testing 2. Completion of the Structured Allergy Questionnaire and Asthma Trigger Inventory 3. Avoidance advice for identified triggers Duration of these was about 30 - 45 minutes. There was no further contact with the nurse until follow up 4 months later.
Intervention type	Other
Primary outcome measure	Lung function/symptoms, assessed at 4 months.
Secondary outcome measures	Self efficacy, assessed at 4 months.
Overall study start date	01/01/2005
Completion date	01/01/2006

Eligibility

Participant type(s)	Patient
Age group	Adult
Sex	Both
Target number of participants	200
Key inclusion criteria	1. Diagnosis of asthma, confirmed by 20% peak expiratory flow [PEF] diurnal variation in medical records or 15% reversibility on spirometry (British Thoracic Society [BTS]/Scottish Intercollegiate Guidelines Network [SIGN] 2003) 2. Prescribed asthma medication within the past year 3. Aged between 16 to 55 years, either sex 4. Not had skin prick testing in the past 10 years
Key exclusion criteria	Unable to give informed consent.
Date of first enrolment	01/01/2005
Date of final enrolment	01/01/2006

Locations

Countries of recruitment

England
United Kingdom

Study participating centre

Centre for Health Sciences

London
E1 4NS
United Kingdom

Sponsor information

St George's Hospital Medical School (UK)
Hospital/treatment centre

Cranmer Terrace
London
SW17 0RE
England
United Kingdom

Website	http://www.sgul.ac.uk/
"ROR"	https://ror.org/040f08y74

Funders

Funder type

Charity

Asthma UK (UK) (ref: 04/016)
Private sector organisation / Other non-profit organizations

Alternative name(s): Asthma UK, Asthma + Lung UK
Location: United Kingdom

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/01/2010		Yes	No