The effects of aspirin on pro-inflammatory response in subjects with diabetes mellitus
| ISRCTN | ISRCTN45751416 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN45751416 |
| Secondary identifying numbers | N0263120034 |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 02/06/2017
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Nutritional, Metabolic, Endocrine
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Vidya Mohamed
Scientific
Scientific
c/o General Medicine
Department of Medicine
Cobbold Labs
Middlesex Hospital
London
W1N 8AA
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | The effects of aspirin on pro-inflammatory response in subjects with diabetes mellitus |
| Study objectives | What effect does aspirin have on IL-6 (interleukin 6)? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Nutritional, Metabolic, Endocrine: Diabetes |
| Intervention | 1. Aspirin 300 mg 2. Aspirin 75 mg 3. Placebo |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | Aspirin |
| Primary outcome measure | Change in IL-6 release in response to aspirin. |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 27/01/2003 |
| Completion date | 01/12/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | 120 patients from the Diabetes Clinic |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 27/01/2003 |
| Date of final enrolment | 01/12/2007 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
c/o General Medicine
London
W1N 8AA
United Kingdom
W1N 8AA
United Kingdom
Sponsor information
Department of Health (UK)
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.doh.gov.uk |
|---|
Funders
Funder type
Government
University College London Hospitals NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Editorial Notes
02/06/2017: No publications found in PubMed, verifying study status with principal investigator
