Contact information
Type
Scientific
Primary contact
Dr Simon Cheung
ORCID ID
Contact details
Department of Medicine
Queen Elizabeth Hospital
30 Gascoigne Road
Kowloon
-
Hong Kong
simoncycheung@gmail.com
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N/A
Study information
Scientific title
Acronym
Study hypothesis
To study whether tacrolimus is superior to cyclosporine in preserving renal function
Ethics approval
Yes, 1998
Study design
Prospective randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Condition
Cadaveric renal transplant
Intervention
Tacrolimus therapy or Neoral cyclosporine therapy
Intervention type
Drug
Phase
Not Specified
Drug names
Tacrolimus and cyclosporine
Primary outcome measure
Patient and graft survival, rejection rate
Secondary outcome measures
Course of renal function, cardiovascular risks, infection and malignancy
Overall trial start date
01/06/1998
Overall trial end date
31/12/2004
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Chinese patients receiving first cadaveric renal transplants consecutively between 01/06/98 and 31/12/04 in Queen Elizabeth Hospital in Hong Kong
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
100
Participant exclusion criteria
Consent not available
Recruitment start date
01/06/1998
Recruitment end date
31/12/2004
Locations
Countries of recruitment
Hong Kong
Trial participating centre
Department of Medicine
Kowloon
-
Hong Kong
Sponsor information
Organisation
Queen Elizabeth Hospital (Hong Kong)
Sponsor details
30
Gascoigne Road
Kowloon
-
Hong Kong
simoncycheung@gmail.com
Sponsor type
Hospital/treatment centre
Website
Funders
Funder type
Hospital/treatment centre
Funder name
Queen Elizabeth Hospital (Hong Kong)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
2006 results in http://www.ncbi.nlm.nih.gov/pubmed/16827683
Publication citations
-
Results
Cheung CY, Wong KM, Chan HW, Liu YL, Chan YH, Wong HS, Chak WL, Choi KS, Chau KF, Li CS, Paired kidney analysis of tacrolimus and cyclosporine microemulsion-based therapy in Chinese cadaveric renal transplant recipients., Transpl. Int., 2006, 19, 8, 657-666, doi: 10.1111/j.1432-2277.2006.00335.x.