Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N/A
Study information
Scientific title
Acronym
Study hypothesis
The purpose of this study is to test the hypothesis that repetitive Transcranial Magnetic Stimulation (rTMS) can attenuate the behavioural response to amphetamine in healthy volunteers.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Condition
Neurosciences, psychiatry
Intervention
rTMS versus sham application (placebo). Both groups receive methamphetamine.
Intervention type
Drug
Phase
Not Specified
Drug names
Methamphetamine
Primary outcome measures
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/03/1999
Overall trial end date
01/03/2000
Reason abandoned
Eligibility
Participant inclusion criteria
1. No significant current or past psychiatric disorder or substance misuse
2. No current physical illness
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
24
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/03/1999
Recruitment end date
01/03/2000
Locations
Countries of recruitment
United Kingdom
Trial participating centre
University Department of Psychiatry
Oxford
OX4 4XN
United Kingdom
Sponsor information
Organisation
Medical Research Council (MRC) (UK)
Sponsor details
20 Park Crescent
London
W1B 1AL
United Kingdom
+44 (0)20 7636 5422
clinical.trial@headoffice.mrc.ac.uk
Sponsor type
Research council
Website
Funders
Funder type
Research council
Funder name
Medical Research Council (UK)
Alternative name(s)
MRC
Funding Body Type
government organisation
Funding Body Subtype
Federal/National Government
Location
United Kingdom
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
2000 results in http://www.ncbi.nlm.nih.gov/pubmed/11343607
Publication citations
-
Results
Clark L, McTavish SF, Harmer CJ, Mills KR, Cowen PJ, Goodwin GM, Repetitive transcranial magnetic stimulation to right prefrontal cortex does not modulate the psychostimulant effects of amphetamine., Int. J. Neuropsychopharmacol., 2000, 3, 4, 297-302, doi: 10.1017/S1461145700002121.