Condition category
Mental and Behavioural Disorders
Date applied
06/04/2000
Date assigned
06/04/2000
Last edited
03/05/2011
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Mr PJ Cowen

ORCID ID

Contact details

University Department of Psychiatry
University of Oxford
Warneford Hospital
Old Road
Headington
Oxford
OX4 4XN
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N/A

Study information

Scientific title

Acronym

Study hypothesis

The purpose of this study is to test the hypothesis that repetitive Transcranial Magnetic Stimulation (rTMS) can attenuate the behavioural response to amphetamine in healthy volunteers.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Condition

Neurosciences, psychiatry

Intervention

rTMS versus sham application (placebo). Both groups receive methamphetamine.

Intervention type

Drug

Phase

Not Specified

Drug names

Methamphetamine

Primary outcome measures

Not provided at time of registration

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/03/1999

Overall trial end date

01/03/2000

Reason abandoned

Eligibility

Participant inclusion criteria

1. No significant current or past psychiatric disorder or substance misuse
2. No current physical illness

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

24

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

01/03/1999

Recruitment end date

01/03/2000

Locations

Countries of recruitment

United Kingdom

Trial participating centre

University Department of Psychiatry
Oxford
OX4 4XN
United Kingdom

Sponsor information

Organisation

Medical Research Council (MRC) (UK)

Sponsor details

20 Park Crescent
London
W1B 1AL
United Kingdom
+44 20 7636 5422
clinical.trial@headoffice.mrc.ac.uk

Sponsor type

Research council

Website

http://www.mrc.ac.uk

Funders

Funder type

Research council

Funder name

Medical Research Council (UK)

Alternative name(s)

MRC

Funding Body Type

private sector organisation

Funding Body Subtype

other non-profit

Location

United Kingdom

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2000 results in http://www.ncbi.nlm.nih.gov/pubmed/11343607

Publication citations

  1. Results

    Clark L, McTavish SF, Harmer CJ, Mills KR, Cowen PJ, Goodwin GM, Repetitive transcranial magnetic stimulation to right prefrontal cortex does not modulate the psychostimulant effects of amphetamine., Int. J. Neuropsychopharmacol., 2000, 3, 4, 297-302, doi: 10.1017/S1461145700002121.

Additional files

Editorial Notes