Effect of rapid transcranial magnetic stimulation (rTMS) on subjective responses to methamphetamine in healthy subjects
| ISRCTN | ISRCTN46614315 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN46614315 |
| Secondary identifying numbers | N/A |
- Submission date
- 06/04/2000
- Registration date
- 06/04/2000
- Last edited
- 03/05/2011
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr PJ Cowen
Scientific
Scientific
University Department of Psychiatry
University of Oxford
Warneford Hospital
Old Road
Headington
Oxford
OX4 4XN
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | |
| Study objectives | The purpose of this study is to test the hypothesis that repetitive Transcranial Magnetic Stimulation (rTMS) can attenuate the behavioural response to amphetamine in healthy volunteers. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Neurosciences, psychiatry |
| Intervention | rTMS versus sham application (placebo). Both groups receive methamphetamine. |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Methamphetamine |
| Primary outcome measure | Not provided at time of registration |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/03/1999 |
| Completion date | 01/03/2000 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | 24 |
| Key inclusion criteria | 1. No significant current or past psychiatric disorder or substance misuse 2. No current physical illness |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/03/1999 |
| Date of final enrolment | 01/03/2000 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
University Department of Psychiatry
Oxford
OX4 4XN
United Kingdom
OX4 4XN
United Kingdom
Sponsor information
Medical Research Council (MRC) (UK)
Research council
Research council
20 Park Crescent
London
W1B 1AL
United Kingdom
| Phone | +44 (0)20 7636 5422 |
|---|---|
| clinical.trial@headoffice.mrc.ac.uk | |
| Website | http://www.mrc.ac.uk |
Funders
Funder type
Research council
Medical Research Council (UK)
Government organisation / National government
Government organisation / National government
- Alternative name(s)
- Medical Research Council (United Kingdom), UK Medical Research Council, MRC
- Location
- United Kingdom
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/12/2000 | Yes | No |
