A randomised controlled trial to evaluate the effectiveness of a pharmacist's telephone reminders in reducing mortality in patients receiving polypharmacy

ISRCTN ISRCTN48076318
DOI https://doi.org/10.1186/ISRCTN48076318
Secondary identifying numbers HSRC/HCPF226103
Submission date
05/10/2004
Registration date
15/02/2005
Last edited
18/02/2008
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Other
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof Juliana CN Chan
Scientific

Dept of Medicine and Therapeutics
Chinese University of Hong Kong
The Prince of Wales Hospital
Shatin
-
-
Hong Kong

Phone +852 (0)2632 3138
Email jchan@cuhk.edu.hk

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Not specified
Study typeTreatment
Scientific title
Study objectivesTo investigate the effects of compliance and periodic telephone counselling by a pharmacist on mortality in patients receiving polypharmacy.
Ethics approval(s)Added as of 22/10/2007:
Ethics approval received from the Chinese University of Hong Kong clinical research ethics committee.
Health condition(s) or problem(s) studiedCompliance to polypharmacy
InterventionPatients randomised to the intervention group received a 10 - 15 minute telephone call from the pharmacist for education and counselling between clinic visits for 2 years. Patients in the control group did not receive any telephone reminders.
Intervention typeOther
Primary outcome measureTime from randomisation to death from any cause.
Secondary outcome measures1. Changes in the rate of admission to hospital
2. Number of emergency room visits
3. Hospital stay in the two years before and after the screening visit
4. Changes in compliance
Overall study start date01/10/1998
Completion date01/06/1999

Eligibility

Participant type(s)Patient
Age groupAdult
SexBoth
Target number of participantsAdded as of 22/10/2007: 502 recruited
Key inclusion criteriaPatients receiving polypharmacy defined as five or more chronic medications who were found to be non-compliant upon first assessment by pharmacist
Key exclusion criteria1. Speak non-Cantonese dialects or a different language
2. Conditions that prevented effective communication (for example, patients who are deaf, mute, or have dementia or other psychological disorders)
3. Live in nursing homes with supervised treatment
Date of first enrolment01/10/1998
Date of final enrolment01/06/1999

Locations

Countries of recruitment

  • Hong Kong

Study participating centre

Dept of Medicine and Therapeutics
-
-
Hong Kong

Sponsor information

Hong Kong Health Services Research Fund (Hong Kong)
Government

Health Welfare and Food Bureau
Government Secretariat, HKSAR
20th floor Murray Building
Garden Road
-
-
Hong Kong

Phone +852 (0)2973 8288
Email hsrf@hwfb.gov.hk
Website http://www.fhb.gov.hk/index.html
ROR logo "ROR" https://ror.org/03qh32912

Funders

Funder type

Government

Hong Kong SAR Government Health Services Research Committee (Hong Kong)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article Results 09/09/2006 Yes No