Condition category
Not Applicable
Date applied
05/10/2004
Date assigned
15/02/2005
Last edited
18/02/2008
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Prof Juliana CN Chan

ORCID ID

Contact details

Dept of Medicine and Therapeutics
Chinese University of Hong Kong
The Prince of Wales Hospital
Shatin
-
-
Hong Kong
+852 (0)2632 3138
jchan@cuhk.edu.hk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

HSRC/HCPF226103

Study information

Scientific title

Acronym

Study hypothesis

To investigate the effects of compliance and periodic telephone counselling by a pharmacist on mortality in patients receiving polypharmacy.

Ethics approval

Added as of 22/10/2007:
Ethics approval received from the Chinese University of Hong Kong clinical research ethics committee.

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Treatment

Patient information sheet

Condition

Compliance to polypharmacy

Intervention

Patients randomised to the intervention group received a 10 - 15 minute telephone call from the pharmacist for education and counselling between clinic visits for 2 years. Patients in the control group did not receive any telephone reminders.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Time from randomisation to death from any cause.

Secondary outcome measures

1. Changes in the rate of admission to hospital
2. Number of emergency room visits
3. Hospital stay in the two years before and after the screening visit
4. Changes in compliance

Overall trial start date

01/10/1998

Overall trial end date

01/06/1999

Reason abandoned

Eligibility

Participant inclusion criteria

Patients receiving polypharmacy defined as five or more chronic medications who were found to be non-compliant upon first assessment by pharmacist

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

Added as of 22/10/2007: 502 recruited

Participant exclusion criteria

1. Speak non-Cantonese dialects or a different language
2. Conditions that prevented effective communication (for example, patients who are deaf, mute, or have dementia or other psychological disorders)
3. Live in nursing homes with supervised treatment

Recruitment start date

01/10/1998

Recruitment end date

01/06/1999

Locations

Countries of recruitment

Hong Kong

Trial participating centre

Dept of Medicine and Therapeutics
-
-
Hong Kong

Sponsor information

Organisation

Hong Kong Health Services Research Fund (Hong Kong)

Sponsor details

Health Welfare and Food Bureau
Government Secretariat
HKSAR
20th floor Murray Building
Garden Road
-
-
Hong Kong
+852 (0)2973 8288
hsrf@hwfb.gov.hk

Sponsor type

Government

Website

http://www.fhb.gov.hk/index.html

Funders

Funder type

Government

Funder name

Hong Kong SAR Government Health Services Research Committee (Hong Kong)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Results in http://www.ncbi.nlm.nih.gov/pubmed/16916809

Publication citations

  1. Results

    Wu JY, Leung WY, Chang S, Lee B, Zee B, Tong PC, Chan JC, Effectiveness of telephone counselling by a pharmacist in reducing mortality in patients receiving polypharmacy: randomised controlled trial., BMJ, 2006, 333, 7567, 522, doi: 10.1136/bmj.38905.447118.2F.

Additional files

Editorial Notes