Psychological treatments of post-traumatic stress disorder
ISRCTN | ISRCTN48524925 |
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DOI | https://doi.org/10.1186/ISRCTN48524925 |
Secondary identifying numbers | 069777 |
- Submission date
- 22/07/2005
- Registration date
- 22/07/2005
- Last edited
- 25/04/2014
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Anke Ehlers
Scientific
Scientific
King's College London
Institute of Psychiatry
Department of Psychology, PO77
De Crespigny Park
London
SE5 8AF
United Kingdom
Phone | +44 (0)20 7848 5033 |
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a.ehlers@iop.kcl.ac.uk |
Study information
Study design | Randomised controlled trial |
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Primary study design | Interventional |
Secondary study design | Randomised controlled trial |
Study setting(s) | Other |
Study type | Treatment |
Scientific title | A randomised controlled trial of weekly and intensive cognitive therapy for post-traumatic stress disorder and supportive therapy |
Study objectives | To compare the efficacy of cognitive therapy for Post-Traumatic Stress Disorder (PTSD), delivered either in weekly sessions or as a one-week intensive treatment, with supportive therapy and a wait list. |
Ethics approval(s) | 1. The South London and Maudsley NHS Trust/Institute of Psychiatry Ethical Committee (Research) (ref: 197/03) 2. Oxfordshire Psychiatric Research Ethics Committee (ref: O03.038) |
Health condition(s) or problem(s) studied | Post-traumatic stress disorder (PTSD) |
Intervention | Four conditions (N = 30 patients with PTSD each): 1. Weekly cognitive therapy for PTSD (12 weekly sessions and up to three monthly booster sessions) 2. Intensive cognitive therapy for PTSD, matched for therapist time 3. Supportive therapy, matched for therapist time 4. 14-week wait list Second site is Oxford University, Department of Psychiatry. |
Intervention type | Other |
Primary outcome measure | Severity of Posttraumatic Stress Disorder (independent assessments and self-report). |
Secondary outcome measures | 1. Depression 2. Anxiety 3. Disability 4. Quality of life |
Overall study start date | 01/11/2003 |
Completion date | 31/03/2008 |
Eligibility
Participant type(s) | Patient |
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Age group | Adult |
Lower age limit | 18 Years |
Sex | Both |
Target number of participants | 120 |
Key inclusion criteria | 1. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) diagnosis of PTSD following discrete traumatic events in adulthood 2. PTSD is main problem 3. 18 to 65 years old, either sex |
Key exclusion criteria | 1. Borderline personality disorder 2. Psychosis 3. Current substance dependence 4. Ongoing severe threat (e.g. still living with perpetrator) 5. Treatment cannot be conducted without the aid of an interpreter 6. Not willing to accept random allocation |
Date of first enrolment | 01/11/2003 |
Date of final enrolment | 31/03/2008 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
King's College London
London
SE5 8AF
United Kingdom
SE5 8AF
United Kingdom
Sponsor information
King's College London (UK)
University/education
University/education
Institute of Psychiatry
De Crespigny Park
London
SE5 8AF
England
United Kingdom
g.dale@iop.kcl.ac.uk | |
https://ror.org/0220mzb33 |
Funders
Funder type
Charity
The Wellcome Trust (UK) (grant ref: 069777)
No information available
Results and Publications
Intention to publish date | |
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Individual participant data (IPD) Intention to share | No |
IPD sharing plan summary | Not provided at time of registration |
Publication and dissemination plan | Not provided at time of registration |
IPD sharing plan |
Study outputs
Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
---|---|---|---|---|---|
Results article | results | 01/03/2014 | Yes | No |