Condition category
Respiratory
Date applied
02/07/2008
Date assigned
10/07/2008
Last edited
30/10/2008
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Andreas Karabinis

ORCID ID

Contact details

Intensive Care Unit
General Hospital of Athens
154 Mesogeion Ave
Athens
11527
Greece
+30 21 0748 0188
echolabicu@gmail.com

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

Artifact2008

Study information

Scientific title

The "cardiac-lung mass" artifact: an echocardiographic sign of lung atelectasis and/or pleural effusion

Acronym

Study hypothesis

We performed an ultrasound study to investigate echocardiographic artifacts in mechanically ventilated patients with lung pathology, based upon the incidental discovery of such findings in five critically ill patients.

Ethics approval

Ethics approval received from the Institutional Ethics Committee of the General Hospital of Athens Intensive Care Unit in August 2005 (ref: 006/08).

Study design

Observational progressive ultrasound study

Primary study design

Observational

Secondary study design

Cohort study

Trial setting

Hospitals

Trial type

Screening

Patient information sheet

Condition

Lung atelectasis or consolidation, and/or pleural effusion

Intervention

Subjects underwent lung echography and transthoracic echocardiography (TTE) with a Philips XD11 XE ultrasound device (Philips, Bothell, USA) equipped with a convex 5 to 7 MHz and with a 1.5 to 3.6-MHz wide-angle, phased-array transducer, respectively. Patients were examined by two experienced observers blinded to each others' interpretation.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Occurence of possible echocardiographic artifacts generated by adjacent lung pathology.

Secondary outcome measures

No secondary outcome measures

Overall trial start date

01/01/2005

Overall trial end date

01/01/2008

Reason abandoned

Eligibility

Participant inclusion criteria

1. Critically ill patients (adults, either sex)
2. Body mass index less than 30 kg/m^2
3. Acute Physiology And Chronic Health Evaluation (APACHE II) score less than 25
4. Exhibited the same initial findings on lung echography, lung atelectasis and/or pleural effusion

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

200

Participant exclusion criteria

Mechanically ventilated patients without any signs of lung pathology

Recruitment start date

01/01/2005

Recruitment end date

01/01/2008

Locations

Countries of recruitment

France, Greece

Trial participating centre

Intensive Care Unit
Athens
11527
Greece

Sponsor information

Organisation

General Hospital of Athens (Greece)

Sponsor details

c/o Dr Andreas Karabinis
Intensive Care Unit
154 Mesogeion Ave
Athens
11527
Greece
+30 21 0748 0188
echolabicu@gmail.com

Sponsor type

Hospital/treatment centre

Website

Funders

Funder type

Hospital/treatment centre

Funder name

General State Hospital of Athens (Greece) - Intensive Care Unit

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2008 results in http://www.ncbi.nlm.nih.gov/pubmed/18826590

Publication citations

  1. Results

    Karabinis A, Saranteas T, Karakitsos D, Lichtenstein D, Poularas J, Yang C, Stefanadis C, The 'cardiac-lung mass' artifact: an echocardiographic sign of lung atelectasis and/or pleural effusion., Crit Care, 2008, 12, 5, R122, doi: 10.1186/cc7021.

Additional files

Editorial Notes