Clinical differences between atopic and atopiform dermatitis

ISRCTN ISRCTN49428666
DOI https://doi.org/10.1186/ISRCTN49428666
Secondary identifying numbers NL754, NTR765
Submission date
28/12/2006
Registration date
28/12/2006
Last edited
14/01/2021
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Skin and Connective Tissue Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr E E A Brenninkmeijer
Scientific

Academic Medical Center Amsterdam
Department of Dermatology, A0-223
P.O. Box 22660
Amsterdam
1105 AZ
Netherlands

Phone +31 (0)20 566 2581
Email E.E.Brenninkmeijer@amc.uva.nl

Study information

Study designCase-control study
Primary study designObservational
Secondary study designCase-control study
Study setting(s)Not specified
Study typeTreatment
Scientific titleClinical differences between atopic and atopiform dermatitis
Study objectivesWe hypothesise that AtopiForm Dermatitis (AFD) is a separate entity with specific characteristics, which needs recognition in order to be diagnosed and treated appropriately.
Ethics approval(s)Approval received from the Medical Ethical Committee (Medisch Ethische Commissie) on the 24th August 2005 (ref: MEC05/171).
Health condition(s) or problem(s) studiedAtopic dermatitis , Atopiform dermatitis
Intervention1. Percutaneous skin prick test
2. Phadiatop blood test
3. SCORing Atopic Dermatitis (SCORAD), Eczema Area and Severity Index (EASI)
4. Diagnositic criteria: Hanifin and Rajka, United Kingdom working party's and Millennium criteria
5. Medical History
6. Quality of life: skindex-29 questionnaire and Short Form health survey (SF-36)
Intervention typeOther
Primary outcome measureAFD (without allergen-specific IgE) is a separate entity with different, specific characteristics compared to AD (with allergen-specific IgE).
Secondary outcome measuresGain more information about the clinical aspects of AFD.
Overall study start date01/03/2006
Completion date22/12/2006

Eligibility

Participant type(s)Patient
Age groupNot Specified
SexBoth
Target number of participants130
Key inclusion criteria1. Written informed consent
2. Age: over two years old
3. Male and female patients
4. Clinical diagnosis of Atopic Dermatitis (AD)
5. Cases: former negative or unknown allergen-specific Immunoglobulin E (IgE) levels in blood
6. Controls: former positive or unknown allergen-specific IgE levels in blood
Key exclusion criteria1. Other skin diseases, which interfere the study
2. Patients unable to comply with the requirements of the study
3. Treatment with systemic corticosteroids or phototherapy within four weeks before performing the skin prick test
4. Treatment with oral anti-histamines within 48-hour before performing the skin prick test
Date of first enrolment01/03/2006
Date of final enrolment22/12/2006

Locations

Countries of recruitment

  • Netherlands

Study participating centre

Academic Medical Center Amsterdam
Amsterdam
1105 AZ
Netherlands

Sponsor information

Academic Medical Center (AMC) (The Netherlands)
Hospital/treatment centre

Department of Dermatology
P.O. Box 22660
Amsterdam
1100 DD
Netherlands

Website http://www.amc.uva.nl/
ROR logo "ROR" https://ror.org/03t4gr691

Funders

Funder type

Not defined

Not provided at time of registration

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article results 01/03/2008 14/01/2021 Yes No

Editorial Notes

14/01/2021: The following changes have been made:
1. Publication reference added.
2. The NTR numbers have been added.