Clinical differences between atopic and atopiform dermatitis
ISRCTN | ISRCTN49428666 |
---|---|
DOI | https://doi.org/10.1186/ISRCTN49428666 |
Secondary identifying numbers | NL754, NTR765 |
- Submission date
- 28/12/2006
- Registration date
- 28/12/2006
- Last edited
- 14/01/2021
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Skin and Connective Tissue Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr E E A Brenninkmeijer
Scientific
Scientific
Academic Medical Center Amsterdam
Department of Dermatology, A0-223
P.O. Box 22660
Amsterdam
1105 AZ
Netherlands
Phone | +31 (0)20 566 2581 |
---|---|
E.E.Brenninkmeijer@amc.uva.nl |
Study information
Study design | Case-control study |
---|---|
Primary study design | Observational |
Secondary study design | Case-control study |
Study setting(s) | Not specified |
Study type | Treatment |
Scientific title | Clinical differences between atopic and atopiform dermatitis |
Study objectives | We hypothesise that AtopiForm Dermatitis (AFD) is a separate entity with specific characteristics, which needs recognition in order to be diagnosed and treated appropriately. |
Ethics approval(s) | Approval received from the Medical Ethical Committee (Medisch Ethische Commissie) on the 24th August 2005 (ref: MEC05/171). |
Health condition(s) or problem(s) studied | Atopic dermatitis , Atopiform dermatitis |
Intervention | 1. Percutaneous skin prick test 2. Phadiatop blood test 3. SCORing Atopic Dermatitis (SCORAD), Eczema Area and Severity Index (EASI) 4. Diagnositic criteria: Hanifin and Rajka, United Kingdom working party's and Millennium criteria 5. Medical History 6. Quality of life: skindex-29 questionnaire and Short Form health survey (SF-36) |
Intervention type | Other |
Primary outcome measure | AFD (without allergen-specific IgE) is a separate entity with different, specific characteristics compared to AD (with allergen-specific IgE). |
Secondary outcome measures | Gain more information about the clinical aspects of AFD. |
Overall study start date | 01/03/2006 |
Completion date | 22/12/2006 |
Eligibility
Participant type(s) | Patient |
---|---|
Age group | Not Specified |
Sex | Both |
Target number of participants | 130 |
Key inclusion criteria | 1. Written informed consent 2. Age: over two years old 3. Male and female patients 4. Clinical diagnosis of Atopic Dermatitis (AD) 5. Cases: former negative or unknown allergen-specific Immunoglobulin E (IgE) levels in blood 6. Controls: former positive or unknown allergen-specific IgE levels in blood |
Key exclusion criteria | 1. Other skin diseases, which interfere the study 2. Patients unable to comply with the requirements of the study 3. Treatment with systemic corticosteroids or phototherapy within four weeks before performing the skin prick test 4. Treatment with oral anti-histamines within 48-hour before performing the skin prick test |
Date of first enrolment | 01/03/2006 |
Date of final enrolment | 22/12/2006 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
Academic Medical Center Amsterdam
Amsterdam
1105 AZ
Netherlands
1105 AZ
Netherlands
Sponsor information
Academic Medical Center (AMC) (The Netherlands)
Hospital/treatment centre
Hospital/treatment centre
Department of Dermatology
P.O. Box 22660
Amsterdam
1100 DD
Netherlands
Website | http://www.amc.uva.nl/ |
---|---|
https://ror.org/03t4gr691 |
Funders
Funder type
Not defined
Not provided at time of registration
No information available
Results and Publications
Intention to publish date | |
---|---|
Individual participant data (IPD) Intention to share | No |
IPD sharing plan summary | Not provided at time of registration |
Publication and dissemination plan | Not provided at time of registration |
IPD sharing plan |
Study outputs
Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
---|---|---|---|---|---|
Results article | results | 01/03/2008 | 14/01/2021 | Yes | No |
Editorial Notes
14/01/2021: The following changes have been made:
1. Publication reference added.
2. The NTR numbers have been added.