Condition category
Respiratory
Date applied
16/06/2010
Date assigned
30/07/2010
Last edited
19/09/2013
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Nicholas Hopkinson

ORCID ID

Contact details

Royal Brompton Hospital
Fulham Road
London
SW3 6NP
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

V1 15-12-09

Study information

Scientific title

The chronic obstructive pulmonary disease (COPD) assessment test in pulmonary rehabilitation: a prospective, multicentre cohort study

Acronym

CATerPillaR study

Study hypothesis

To establish what changes in chronic obstructive pulmonary disease assessment test (CAT) occur after pulmonary rehabilitation and relate these to changes in other parameters that are routinely measured.

Ethics approval

Riverside Research Ethics Committee approved on the 11th March 2010 (ref: 10/H0706/15)

Study design

Prospective cohort study

Primary study design

Observational

Secondary study design

Cohort study

Trial setting

Hospitals

Trial type

Diagnostic

Patient information sheet

Not available in web format, please use the contact details below to request a patient information sheet

Condition

Chronic obstructive pulmonary disease

Intervention

Prospective collection of routinely collected, anonymised, outcome data including the COPD assessment test score (CAT) from several pulmonary rehabilitation programs.

Pulmonary rehabilitation is a program of supervised exercise and education, usually lasting about 8 weeks designed to improve symptoms and functional capacity for patients with respiratory disease. Measures of quality of life and walking distance are taken at baseline and after the course to assess response routinely.

Intervention type

Other

Phase

Not Applicable

Drug names

Primary outcome measures

Change in CAT score versus anchor score of self-reported improvement 1 - 5

Secondary outcome measures

1. Change in CAT score versus walking distance
2. Change in CAT score versus St George's Respiratory Questionnaire (SGRQ)
3. Change in CAT score versus Chronic Respiratory Disease Questionnaire (CRQ)

Overall trial start date

01/01/2010

Overall trial end date

01/09/2010

Reason abandoned

Eligibility

Participant inclusion criteria

1. Patients aged greater than 21 years, either sex
2. With COPD
3. Participating in pulmonary rehabilitation

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

200

Participant exclusion criteria

Major co-morbidity limiting exercise

Recruitment start date

01/01/2010

Recruitment end date

01/09/2010

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Royal Brompton Hospital
London
SW3 6NP
United Kingdom

Sponsor information

Organisation

Imperial College London (UK)

Sponsor details

Clinical Research Governance Office
Sir Alexander Fleming Building
Exhibition Road
London
SW7 2AZ
United Kingdom

Sponsor type

University/education

Website

http://www3.imperial.ac.uk/clinicalresearchgovernanceoffice

Funders

Funder type

Research organisation

Funder name

NIHR Respiratory Disease Biomedical Research Unit (UK) - supported by Royal Brompton and Harefield NHS Foundation Trust and Imperial College London

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2011 results in: http://www.ncbi.nlm.nih.gov/pubmed/21398686

Publication citations

  1. Results

    Dodd JW, Hogg L, Nolan J, Jefford H, Grant A, Lord VM, Falzon C, Garrod R, Lee C, Polkey MI, Jones PW, Man WD, Hopkinson NS, The COPD assessment test (CAT): response to pulmonary rehabilitation. A multicentre, prospective study., Thorax, 2011, 66, 5, 425-429, doi: 10.1136/thx.2010.156372.

Additional files

Editorial Notes