Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
V1 15-12-09
Study information
Scientific title
The chronic obstructive pulmonary disease (COPD) assessment test in pulmonary rehabilitation: a prospective, multicentre cohort study
Acronym
CATerPillaR study
Study hypothesis
To establish what changes in chronic obstructive pulmonary disease assessment test (CAT) occur after pulmonary rehabilitation and relate these to changes in other parameters that are routinely measured.
Ethics approval
Riverside Research Ethics Committee approved on the 11th March 2010 (ref: 10/H0706/15)
Study design
Prospective cohort study
Primary study design
Observational
Secondary study design
Cohort study
Trial setting
Hospitals
Trial type
Diagnostic
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Condition
Chronic obstructive pulmonary disease
Intervention
Prospective collection of routinely collected, anonymised, outcome data including the COPD assessment test score (CAT) from several pulmonary rehabilitation programs.
Pulmonary rehabilitation is a program of supervised exercise and education, usually lasting about 8 weeks designed to improve symptoms and functional capacity for patients with respiratory disease. Measures of quality of life and walking distance are taken at baseline and after the course to assess response routinely.
Intervention type
Other
Phase
Not Applicable
Drug names
Primary outcome measures
Change in CAT score versus anchor score of self-reported improvement 1 - 5
Secondary outcome measures
1. Change in CAT score versus walking distance
2. Change in CAT score versus St George's Respiratory Questionnaire (SGRQ)
3. Change in CAT score versus Chronic Respiratory Disease Questionnaire (CRQ)
Overall trial start date
01/01/2010
Overall trial end date
01/09/2010
Reason abandoned
Eligibility
Participant inclusion criteria
1. Patients aged greater than 21 years, either sex
2. With COPD
3. Participating in pulmonary rehabilitation
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
200
Participant exclusion criteria
Major co-morbidity limiting exercise
Recruitment start date
01/01/2010
Recruitment end date
01/09/2010
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Royal Brompton Hospital
London
SW3 6NP
United Kingdom
Sponsor information
Organisation
Imperial College London (UK)
Sponsor details
Clinical Research Governance Office
Sir Alexander Fleming Building
Exhibition Road
London
SW7 2AZ
United Kingdom
Sponsor type
University/education
Website
Funders
Funder type
Research organisation
Funder name
NIHR Respiratory Disease Biomedical Research Unit (UK) - supported by Royal Brompton and Harefield NHS Foundation Trust and Imperial College London
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
2011 results in: http://www.ncbi.nlm.nih.gov/pubmed/21398686
Publication citations
-
Results
Dodd JW, Hogg L, Nolan J, Jefford H, Grant A, Lord VM, Falzon C, Garrod R, Lee C, Polkey MI, Jones PW, Man WD, Hopkinson NS, The COPD assessment test (CAT): response to pulmonary rehabilitation. A multicentre, prospective study., Thorax, 2011, 66, 5, 425-429, doi: 10.1136/thx.2010.156372.