Suction versus non-suction technique in fine aspiration cytology of thyroid lumps: a single blind randomised trial

ISRCTN	ISRCTN51730344
DOI	https://doi.org/10.1186/ISRCTN51730344
Secondary identifying numbers	N/A

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Mr Yohanna M Takwoingi
Scientific

Department of Otolaryngology
City Hospital
Birmingham
B18 7QH
United Kingdom

Phone	+44 (0)121 5074559

Study design	A single blind randomised controlled study: study allocation numbers will be concealed in opaque enevelopes and slides will be blinded to the pathologist
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Diagnostic
Scientific title
Study acronym	FNAC in thyroid lumps
Study objectives	Does obtaining samples by non-suction technique give similar or better results than the suction method?
Ethics approval(s)	Local Research Ethics Committee, 27/10/2005
Health condition(s) or problem(s) studied	Multiple or single thyroid nodules
Intervention	Diseased thyoid tissue will be aspirated for cytological study using a fine bore needle
Intervention type	Other
Primary outcome measure	1. Good quality slides for laboratory examination 2. To find the test that gives the highest yield of accurate results
Secondary outcome measures	1. All slides will be scored based on the amount of bloodstaining, cellularity and preservation of the cells 2. Patient satisfaction would be surveyed using a questionnaire
Overall study start date	07/02/2006
Completion date	31/07/2007

Participant type(s)	Patient
Age group	Adult
Sex	Both
Target number of participants	280 patients
Key inclusion criteria	All patients referred to the Thyroid Lump Clinic, City Hospital, Birmingham
Key exclusion criteria	1. Children under 16 years of age 2. Patients unable to give consent for the study 3. Adults in emergency situations
Date of first enrolment	07/02/2006
Date of final enrolment	31/07/2007

Department of Otolaryngology

Birmingham
B18 7QH
United Kingdom

Sandwell and West Birmingham Hospitals NHS Trust (UK)
Hospital/treatment centre

Research and Development
Arden House
City Hospital
Birmingham
B18 7QH
England
United Kingdom

Government

Sandwell and West Birmingham Hospitals NHS Trust

No information available

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan