Randomised trial of primary systemic therapy versus conventional therapy in operable breast cancer
| ISRCTN | ISRCTN52587283 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN52587283 |
| Secondary identifying numbers | SCTO37 |
- Submission date
- 19/08/2002
- Registration date
- 19/08/2002
- Last edited
- 24/10/2019
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Cancer
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr - -
Scientific
Scientific
UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | Randomised trial of primary systemic therapy versus conventional therapy in operable breast cancer |
| Study objectives | Not provided at time of registration |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Breast |
| Intervention | 1. Group A: Mastectomy, wide local excision and axillary clearance plus adjuvant tamoxifen or CMF chemotherapy (depending on menstrual and nodal status) 2. Group B: Primary systemic therapy either endocrine or CAP chemotherapy (depending on oestrogen receptor status) followed by mastectomy, wide local excision and axillary clearance, and adjuvant endocrine or chemotherapy depending on prior response of tumour |
| Intervention type | Other |
| Primary outcome measure | Not provided at time of registration |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/01/1990 |
| Completion date | 31/10/1995 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Female |
| Target number of participants | Not provided at time of registration |
| Key inclusion criteria | 1. Operable carcinoma of the breast 2. Age <70 years 3. No medical contraindications to protocol treatments |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/01/1990 |
| Date of final enrolment | 31/10/1995 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
UKCCCR Register Co-ordinator
London
NW1 2DA
United Kingdom
NW1 2DA
United Kingdom
Sponsor information
Scottish Cancer Therapy Network (UK)
Research organisation
Research organisation
Trinity Park House
South Trinity Road
Edinburgh
EH5 3SQ
United Kingdom
Funders
Funder type
Research organisation
Scottish Therapy Network (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Editorial Notes
24/10/2019: No publications found. All search options exhausted.
