Contact information
Type
Scientific
Primary contact
Prof Stefan Priebe
ORCID ID
Contact details
Unit for Community and Social Psychiatry
Newham Centre for Mental Health
Cherry Tree Way
Glen Road
Plaistow
London
E13 8SP
United Kingdom
+44 (0)20 7540 4210
s.priebe@qmul.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
PB-PG-0906-10540
Study information
Scientific title
Acronym
DIALECT
Study hypothesis
Self-harming patients receiving a one-year course of dialectical behaviour therapy (DBT) will self-harm less over the 12 months than patients receiving one year of treatment as usual.
Ethics approval
The Camden and Islington Community Local Research Ethics Committee, 18/02/2008, ref: 07/H0722/98
Study design
Pilot randomised controlled pragmatic exploratory trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Condition
Borderline personality disorder, self-harm
Intervention
DBT and care co-ordination versus waiting list control group with standard NHS care, over 12 months. DBT consists of 3 hours of therapy a week: this comprises 1 hour of individual therapy and 2 hours of group skills classes.
Intervention type
Other
Phase
Not Applicable
Drug names
Primary outcome measures
Days with self-harm during the 12-month period.
Secondary outcome measures
1. Pre-post changes in self-harming during the 12-month period
2. Number of accident and emergency (A&E) attendances during the 12-month period
3. Inpatient admissions during the 12-month period
4. Use of other services in primary and secondary care during the 12-month period
5. Service costs during the 12-month period
6. Use of medication during the 12-month period
7. Pre-post changes in self-rated and observer-rated symptom level and quality of life at the end of the 12 month period
8. Quality of the therapeutic relationship at the end of the 12-month period
9. Treatment satisfaction at the end of the 12-month period
Overall trial start date
01/02/2008
Overall trial end date
01/07/2011
Reason abandoned
Eligibility
Participant inclusion criteria
1. Frequent self-harm (more than 5 days with self-harm over 12 months)
2. Aged 16 years and older, either sex
3. Sufficient command of English
4. At least one personality disorder
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
60
Participant exclusion criteria
Learning disabilities
Recruitment start date
01/02/2008
Recruitment end date
01/07/2011
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Unit for Community and Social Psychiatry
London
E13 8SP
United Kingdom
Sponsor information
Organisation
East London NHS Foundation Trust (UK)
Sponsor details
Trust Headquarters
EastONE
22 Commercial Street
London
E1 6LP
United Kingdom
+44 (0)20 7655 4000
webadmin@eastlondon.nhs.uk
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
National Institute for Health Research (NIHR) (UK) - Research for Patient Benefit (RfPB) Programme
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
2012 results in: http://www.ncbi.nlm.nih.gov/pubmed/22964561
Publication citations
-
Results
Priebe S, Bhatti N, Barnicot K, Bremner S, Gaglia A, Katsakou C, Molosankwe I, McCrone P, Zinkler M, Effectiveness and cost-effectiveness of dialectical behaviour therapy for self-harming patients with personality disorder: a pragmatic randomised controlled trial., Psychother Psychosom, 2012, 81, 6, 356-365, doi: 10.1159/000338897.