Proton pump inhibitor (PPI) treatment of gastro-oesophageal reflux (GOR) associated with non-cardiac chest pain (NCCP)

ISRCTN	ISRCTN56363424
DOI	https://doi.org/10.1186/ISRCTN56363424
Secondary identifying numbers	N0123138371

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Dr Peter Wurm
Scientific

University Hospitals of Leicester
c/o Research and Development Office
Leicester General Hospital NHS Trust
Leicester
LE1 4PW
United Kingdom

Phone	+44 (0)116 258 4109
Email	nicola.turner@uhl-tr.nhs.uk

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Not specified
Study type	Treatment
Scientific title	Proton pump inhibitor (PPI) treatment of gastro-oesophageal reflux (GOR) associated with non-cardiac chest pain (NCCP)
Study objectives	1. To investigate the efficacy of a proton pump inhibitor (PPI) (omeprazole 40 mg) of non-cardiac chest pain (NCCP) in patients with pH-metric evidence of abnormal gastro-oesophageal reflux (GOR) 2. To clarify which factor - endoscopic oesophagitis, positive symptom index, positive acid perfusion test - best identifies patients
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Gastro-oesophageal reflux disease (GORD)
Intervention	Randomised controlled trial
Intervention type	Other
Primary outcome measure	Proton pump inhibitor treatment of gastro-oesophageal reflux (GOR) associated with non cardiac chest pain (NCCP)
Secondary outcome measures	Not provided at time of registration
Overall study start date	01/08/2002
Completion date	01/04/2003

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target number of participants	Not provided at time of registration
Key inclusion criteria	Patients associated with non cardiac chest pain
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	01/08/2002
Date of final enrolment	01/04/2003

University Hospitals of Leicester

Leicester
LE1 4PW
United Kingdom

Department of Health
Government

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Website	http://www.dh.gov.uk/Home/fs/en

Government

University Hospitals of Leicester NHS Trust (UK)

No information available

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/07/2010		Yes	No

28/07/2017: Publication reference added.