Contact information
Type
Scientific
Primary contact
Dr Peter Wurm
ORCID ID
Contact details
University Hospitals of Leicester
c/o Research and Development Office
Leicester General Hospital NHS Trust
Leicester
LE1 4PW
United Kingdom
+44 (0)116 258 4109
nicola.turner@uhl-tr.nhs.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0123138371
Study information
Scientific title
Proton pump inhibitor (PPI) treatment of gastro-oesophageal reflux (GOR) associated with non-cardiac chest pain (NCCP)
Acronym
Study hypothesis
1. To investigate the efficacy of a proton pump inhibitor (PPI) (omeprazole 40 mg) of non-cardiac chest pain (NCCP) in patients with pH-metric evidence of abnormal gastro-oesophageal reflux (GOR)
2. To clarify which factor - endoscopic oesophagitis, positive symptom index, positive acid perfusion test - best identifies patients
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Treatment
Patient information sheet
Condition
Gastro-oesophageal reflux disease (GORD)
Intervention
Randomised controlled trial
Intervention type
Other
Phase
Not Applicable
Drug names
Primary outcome measures
Proton pump inhibitor treatment of gastro-oesophageal reflux (GOR) associated with non cardiac chest pain (NCCP)
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/08/2002
Overall trial end date
01/04/2003
Reason abandoned
Eligibility
Participant inclusion criteria
Patients associated with non cardiac chest pain
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
Not provided at time of registration
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/08/2002
Recruitment end date
01/04/2003
Locations
Countries of recruitment
United Kingdom
Trial participating centre
University Hospitals of Leicester
Leicester
LE1 4PW
United Kingdom
Sponsor information
Organisation
Department of Health
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
University Hospitals of Leicester NHS Trust (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
2010 results in https://www.ncbi.nlm.nih.gov/pubmed/20456303