Condition category
Circulatory System
Date applied
30/11/2010
Date assigned
05/07/2011
Last edited
04/02/2016
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Prof Gavin Perkins

ORCID ID

Contact details

Warwick Medical School Clinical Trials Unit
University of Warwick
Coventry
CV4 7AL
United Kingdom
-
g.d.perkins@warwick.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

PB-PG-1207-14246

Study information

Scientific title

Cardiopulmonary resuscitation (CPR) quality improvement programme: a multicentre, prospective, cohort study

Acronym

Study hypothesis

Implementing a CPR quality improvement initiative will improve the rate of return of spontaneous circulation and other outcomes in patients sustaining cardiac arrest

Ethics approval

Coventry Research Ethics Committee, 26/06/2009, REC ref: 09/H1210/65

Study design

Multicentre prospective cohort study

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Not available in web format, please use the contact details below to request a patient information sheet.

Condition

In-hospital cardiac arrests

Intervention

1. Control
2. CPR feedback through Q-CPR® (Laerdal medical, UK)
3. CPR feedback through Q-CPR® (Laerdal medical, UK) plus team briefing / debriefing

Intervention type

Other

Phase

Not Applicable

Drug names

Primary outcome measures

Survived event [defined as sustained (> 20 minutes) return of spontaneous circulation]

Secondary outcome measures

1. Patient outcomes
1.1. Any return of spontaneous circulation
1.2. Survival to hospital discharge
1.3. Cerebral performance category of patients at discharge
2. Process outcomes
2.1. Quality of emergency calls
2.2. Chest compression depth, rate
2.3. No flow time
2.4. Duration of pre and post-shock pauses
2.5. Ventilation rate
2.6. time to first shock
2.7.Appropriate decision to shock
3. Team factors
3.1. CPR knowledge
3.2. Confidence / preparedness

Overall trial start date

01/11/2009

Overall trial end date

31/01/2013

Reason abandoned

Eligibility

Participant inclusion criteria

Patients have to be either 18 or older and suffer an in-hospital cardiac arrest where resuscitation is attempted (defined as loss of a pulse requiring the delivery of chest compressions).

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

912

Participant exclusion criteria

1. Patient has a Do-not-attempt resuscitation order written and documented in their medical records
2. Cardiac arrest not attended by a resuscitation team
3. Out - of - hospital cardiac arrest
4. Previous participation in this study

Recruitment start date

01/11/2009

Recruitment end date

31/01/2013

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Warwick Medical School Clinical Trials Unit
Coventry
CV4 7AL
United Kingdom

Sponsor information

Organisation

Heart of England NHS Foundation Trust (UK)

Sponsor details

c/o Elizabeth Adey
R+D Manager
MIDRU
Bordesley Green East
Birmingham
B9 5SS
United Kingdom
-
Elizabeth.Adey@heartofengland.nhs.uk

Sponsor type

Government

Website

Funders

Funder type

Government

Funder name

National Institute for Health Research (NIHR) (UK) - Research for Patient Benefit (RfPB) programme (PB-PG-1207-14246)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2011 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/22008636
2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/26186567

Publication citations

  1. Protocol

    Perkins GD, Davies RP, Quinton S, Woolley S, Gao F, Abella B, Stallard N, Cooke MW, , The effect of real-time CPR feedback and post event debriefing on patient and processes focused outcomes: a cohort study: trial protocol., Scand J Trauma Resusc Emerg Med, 2011, 19, 58, doi: 10.1186/1757-7241-19-58.

  2. Results

    Couper K, Kimani PK, Abella BS, Chilwan M, Cooke MW, Davies RP, Field RA, Gao F, Quinton S, Stallard N, Woolley S, Perkins GD; Cardiopulmonary Resuscitation Quality Improvement Initiative Collaborators, The System-Wide Effect of Real-Time Audiovisual Feedback and Postevent Debriefing for In-Hospital Cardiac Arrest: The Cardiopulmonary Resuscitation Quality Improvement Initiative, Crit Care Med, 2015, 43, 11, 2321-2331, doi: 10.1097/CCM.0000000000001202.

Additional files

Editorial Notes

04/02/2016: Publication reference added.