Post-operative use of cell savers
| ISRCTN | ISRCTN57101575 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN57101575 |
| Secondary identifying numbers | N0205123739 |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 14/06/2017
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr Alex Shipolini
Scientific
Scientific
Consultant Cardiothoracic Surgeon
Department of Cardiothoracic Surgery
The London Chest Hospital
Bonner Road
London
E2 9JX
United Kingdom
| Phone | +44 (0)20 8983 2322 |
|---|---|
| alex.shipolini@bartsandthelondon.nhs.uk |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | Post-operative use of cell savers |
| Study objectives | To investigate whether the dedeco-electra cell saver reduces homologous transfusion requirements in the post-operative phase and whether in conjunction with leucocyte filtration may reduce inflammation as measured by IL-6, IL8A, IL-10 release a leucocyte activation CD69 and CD11 a (flow cytometry) in the retransfused salvaged blood. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Surgery: Homologous transfusion |
| Intervention | Not provided at time of registration |
| Intervention type | Procedure/Surgery |
| Primary outcome measure | 1. Reduction in requirement for homologous blood transfusion 2. Reduction in flammatory mediators and activated leucocytes in the washed, salvaged autologous red cells |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/05/2003 |
| Completion date | 01/08/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | Not provided at time of registration |
| Key inclusion criteria | Barts and the London NHS Trust patients |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/05/2003 |
| Date of final enrolment | 01/08/2006 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
The London Chest Hospital
London
E2 9JX
United Kingdom
E2 9JX
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.dh.gov.uk/Home/fs/en |
|---|
Funders
Funder type
Hospital/treatment centre
Barts and The London NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Editorial Notes
14/06/2017: No publications found in PubMed, verifying study status with principal investigator
