Contact information
Type
Scientific
Primary contact
Dr Dagmar Slot
ORCID ID
Contact details
Hogeschool INHOLLAND
School of Health
Postvak 32
Louwesweg 1
Amsterdam
1066 EA
Netherlands
+31 (0)20 5188643
Dagmar.Slot@inholland.acta.nl
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
NTR274
Study information
Scientific title
Acronym
DAGMAR - Daily Application of a Gingival Maintenance Antimicrobial Regimen
Study hypothesis
Tray application of 0.12% chlorhexidine gel-toothpaste has more than 15% better effect
on 'de novo' plaque accumulation compared to tray application of regular toothpaste in a 3 day non-brushing model.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Dental plaque
Intervention
Tray application of 0.12% chlorhexidine gel-toothpaste twice daily for 2 minutes or tray application of regular toothpaste twice daily for 2 minutes or rinsing with 0.12% chlorhexidine mouthwash twice daily for 1 minute, during a 3 day non-brushing period.
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measure
Quigley & Hein plaque-index after 3 days (72 hours) of 'de novo' plaque accumulation.
Secondary outcome measures
Results from the visual analogue scale (VAS) questionnaire to evaluate the subject's attitude towards to the used products.
Overall trial start date
19/09/2005
Overall trial end date
03/10/2005
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
1. >=18 years
2. Systemically healthy
3. >=20 teeth
4. 5 teeth per quadrant
5. No pockets >5 mm
6. No orthodontic appliances
7. No removable (partial) dentures
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
90
Participant exclusion criteria
1. Use of medication possibly influencing normal gingival health
2. Pregnancy
Recruitment start date
19/09/2005
Recruitment end date
03/10/2005
Locations
Countries of recruitment
Netherlands
Trial participating centre
Hogeschool INHOLLAND
Amsterdam
1066 EA
Netherlands
Sponsor information
Organisation
Academic Centre for Dentistry in Amsterdam (ACTA) (Netherlands)
Sponsor details
Louwesweg 1
Amsterdam
1066 EA
Netherlands
Sponsor type
University/education
Website
Funders
Funder type
University/education
Funder name
Hogeschool INHOLLAND, School of Health in Diemen, Dentaid Benelux (Netherlands)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
2007 results in http://www.ncbi.nlm.nih.gov/pubmed/17250578
Publication citations
-
Results
Slot DE, Lindeboom R, Rosema NA, Timmerman MF, van der Weijden GA, The effect of 0.12% chlorhexidine dentifrice gel on plaque accumulation: a 3-day non-brushing model., Int J Dent Hyg, 2007, 5, 1, 45-52, doi: 10.1111/j.1601-5037.2007.00227.x.