Condition category
Mental and Behavioural Disorders
Date applied
09/03/2005
Date assigned
26/05/2005
Last edited
16/09/2009
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Carolyn Chew-Graham

ORCID ID

Contact details

Rusholme Academic Unit
Rusholme Health Centre
Walmer Street
Rusholme
Manchester
M14 5NP
United Kingdom
cchew@man.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

0250024

Study information

Scientific title

A controlled trial to investigate the feasibility of a new model of intervention for the treatment of late-life depression in primary care

Acronym

PRIDE

Study hypothesis

The aim of the trial is to test whether the new intervention, delivered in primary care, leads to improved outcomes for elderly depressed people.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

GP practices

Trial type

Treatment

Patient information sheet

Condition

Late-life depression

Intervention

The intervention comprises: antidepressants (where appropriate) prescribed by the general practitioner, a brief psychological intervention delivered by a community psychiatric nurse (CPN) employed by the study, and care management according to a defined algorithm. The CPN is working closely with the patient's general practitioner but the model demands close support from and liaison with the specialist community mental health team for older people.

Control: usual care

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

SCID scores

Secondary outcome measures

Montgomery-asberg scores

Overall trial start date

01/02/2004

Overall trial end date

30/09/2005

Reason abandoned

Eligibility

Participant inclusion criteria

Elderly people (>60) with depression as defined by the GP or community or practice nurse are referred into the study.
If depressed (Geriatric Depression Scale [GDS] %) they are randomised to intervention or usual care group.

Participant type

Patient

Age group

Senior

Gender

Both

Target number of participants

100

Participant exclusion criteria

Does not meet inclusion criteria

Recruitment start date

01/02/2004

Recruitment end date

30/09/2005

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Rusholme Academic Unit
Manchester
M14 5NP
United Kingdom

Sponsor information

Organisation

University of Manchester (UK)

Sponsor details

Oxford Road
Manchester
M13 9PL
United Kingdom
cchew@man.ac.uk

Sponsor type

University/education

Website

Funders

Funder type

Government

Funder name

Department of Health (UK) (ref: 0250024) - the call for bids was 2002, National Service Framework for Older People

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

1. 2006 results in http://www.ncbi.nlm.nih.gov/pubmed/16476699
2. 2007 results in http://www.ncbi.nlm.nih.gov/pubmed/17504586
3. Chew-Graham CA, Lovell K, Roberts C, Baldwin M, Morley M, Burns A,
Burroughs H. Achieving target recruitment in a primary care trial:
lessons from PRIDE. Primary Health Care Research and Development, 2007
8, 3: 264-70.

Publication citations

  1. Results

    Burroughs H, Lovell K, Morley M, Baldwin R, Burns A, Chew-Graham C, 'Justifiable depression': how primary care professionals and patients view late-life depression? A qualitative study., Fam Pract, 2006, 23, 3, 369-377, doi: 10.1093/fampra/cmi115.

  2. Results

    Chew-Graham CA, Lovell K, Roberts C, Baldwin R, Morley M, Burns A, Richards D, Burroughs H, A randomised controlled trial to test the feasibility of a collaborative care model for the management of depression in older people., Br J Gen Pract, 2007, 57, 538, 364-370.

Additional files

Editorial Notes