Individualising exercise for knee pain: developing an evidence-based impairment-targeted intervention

ISRCTN ISRCTN61638364
DOI https://doi.org/10.1186/ISRCTN61638364
Secondary identifying numbers 5142
Submission date
24/06/2010
Registration date
24/06/2010
Last edited
01/02/2016
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Signs and Symptoms
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr Laurence Wood
Scientific

Primary Care Musculoskeletal Research Centre
Keele
Newcastle
ST5 5BG
United Kingdom

Phone +44 1782 733908
Email l.r.j.wood@cphc.keele.ac.uk

Study information

Study designSingle centre non-randomised interventional treatment trial
Primary study designInterventional
Secondary study designNon randomised controlled trial
Study setting(s)GP practice
Study typeTreatment
Scientific titleIndividualising exercise for knee pain: developing an evidence-based impairment-targeted intervention
Study acronymTargET-Knee-Pain
Study objectivesThe overall aim of this study is to investigate the principle of impairment-targeted exercises as treatments for older adults with knee pain. The study has a single-group design. It has the following objectives:

Objective 1:
To test the proof-of-principle that simple home-based impairment-targeted exercises can improve those impairments in older adults with knee pain.

Objective 2:
To investigate whether improvements in these impairments are reflected in improvements in self-reports of physical function.

Objective 3:
To assess the feasibility of this intervention approach and its acceptability to patients by qualitative means.
Ethics approval(s)MREC approved on the 7th November 2008 (ref: 08/H1202/179)
Health condition(s) or problem(s) studiedTopic: Primary Care Research Network for England, Musculoskeletal; Subtopic: Not Assigned, Musculoskeletal (all Subtopics); Disease: Musculoskeletal, All Diseases
InterventionThis will be a single-centre study. Participants will be invited to participate in the current study at the end of their visit for final clinical assessment before the termination of the CAS-K study.

Exercise programme: consists of an individualised home-based impairment-targeted exercise programme for 12 weeks (fortnightly home visits alternating with fortnightly telephone calls) and involves daily self-directed formal exercises.

Recruitment will last for the duration of the final clinical assessment clinics, which are planned to take place between January and December 2009. Duration of follow-up will be 12 weeks.

Study entry: registration only
Intervention typeOther
Primary outcome measureDegree of knee flexion, measured with a continuous scale outcome
Secondary outcome measures1. Isometric quadriceps strength at 90º flexion, measured with a continuous scale outcome
2. The four-test balance scale, measured with an ordinal scale (range 0 - 5), including feet together stand, semi-tandem stand, tandem stand and one-leg stand
Overall study start date05/05/2009
Completion date09/02/2010

Eligibility

Participant type(s)Patient
Age groupSenior
SexBoth
Target number of participantsPlanned sample size: 80; UK sample size: 80
Key inclusion criteria1. Aged 56 years and older, either sex
2. A history of painful osteoarthritis of the knees
3. One or more of the target impairments
4. Recruited from the longitudinal population-based Clinical Assessment Study of the Knee (CAS-K)
Key exclusion criteriaDoes not meet inclusion criteria
Date of first enrolment05/05/2009
Date of final enrolment09/02/2010

Locations

Countries of recruitment

  • England
  • United Kingdom

Study participating centre

Primary Care Musculoskeletal Research Centre
Newcastle
ST5 5BG
United Kingdom

Sponsor information

Keele University (UK)
University/education

Keele
Newcastle
ST5 5BG
England
United Kingdom

Website http://www.keele.ac.uk/
ROR logo "ROR" https://ror.org/00340yn33

Funders

Funder type

Government

National Institute for Health Research (NIHR) (UK) - Research for Patient Benefit (RfPB) programme (ref: PB-PG-0107-10612)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article results 07/01/2011 Yes No
Results article results 29/01/2016 Yes No

Editorial Notes

01/02/2016: Publication reference added, verifying study status with principal investigator.