Individualising exercise for knee pain: developing an evidence-based impairment-targeted intervention
| ISRCTN | ISRCTN61638364 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN61638364 |
| Protocol serial number | 5142 |
| Sponsor | Keele University (UK) |
| Funder | National Institute for Health Research (NIHR) (UK) - Research for Patient Benefit (RfPB) programme (ref: PB-PG-0107-10612) |
- Submission date
- 24/06/2010
- Registration date
- 24/06/2010
- Last edited
- 01/02/2016
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Signs and Symptoms
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Laurence Wood
Scientific
Scientific
Primary Care Musculoskeletal Research Centre
Keele
Newcastle
ST5 5BG
United Kingdom
| Phone | +44 1782 733908 |
|---|---|
| l.r.j.wood@cphc.keele.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Single centre non-randomised interventional treatment trial |
| Secondary study design | Non randomised controlled trial |
| Scientific title | Individualising exercise for knee pain: developing an evidence-based impairment-targeted intervention |
| Study acronym | TargET-Knee-Pain |
| Study objectives | The overall aim of this study is to investigate the principle of impairment-targeted exercises as treatments for older adults with knee pain. The study has a single-group design. It has the following objectives: Objective 1: To test the proof-of-principle that simple home-based impairment-targeted exercises can improve those impairments in older adults with knee pain. Objective 2: To investigate whether improvements in these impairments are reflected in improvements in self-reports of physical function. Objective 3: To assess the feasibility of this intervention approach and its acceptability to patients by qualitative means. |
| Ethics approval(s) | MREC approved on the 7th November 2008 (ref: 08/H1202/179) |
| Health condition(s) or problem(s) studied | Topic: Primary Care Research Network for England, Musculoskeletal; Subtopic: Not Assigned, Musculoskeletal (all Subtopics); Disease: Musculoskeletal, All Diseases |
| Intervention | This will be a single-centre study. Participants will be invited to participate in the current study at the end of their visit for final clinical assessment before the termination of the CAS-K study. Exercise programme: consists of an individualised home-based impairment-targeted exercise programme for 12 weeks (fortnightly home visits alternating with fortnightly telephone calls) and involves daily self-directed formal exercises. Recruitment will last for the duration of the final clinical assessment clinics, which are planned to take place between January and December 2009. Duration of follow-up will be 12 weeks. Study entry: registration only |
| Intervention type | Other |
| Primary outcome measure(s) |
Degree of knee flexion, measured with a continuous scale outcome |
| Key secondary outcome measure(s) |
1. Isometric quadriceps strength at 90º flexion, measured with a continuous scale outcome |
| Completion date | 09/02/2010 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Senior |
| Sex | All |
| Target sample size at registration | 80 |
| Key inclusion criteria | 1. Aged 56 years and older, either sex 2. A history of painful osteoarthritis of the knees 3. One or more of the target impairments 4. Recruited from the longitudinal population-based Clinical Assessment Study of the Knee (CAS-K) |
| Key exclusion criteria | Does not meet inclusion criteria |
| Date of first enrolment | 05/05/2009 |
| Date of final enrolment | 09/02/2010 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Primary Care Musculoskeletal Research Centre
Newcastle
ST5 5BG
United Kingdom
ST5 5BG
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 07/01/2011 | Yes | No | |
| Results article | results | 29/01/2016 | Yes | No |
Editorial Notes
01/02/2016: Publication reference added, verifying study status with principal investigator.
