Evaluation of equivalent effective dose of ephedrine and phenylephrine in prevention of hypotension after spinal anaesthesia for caesarean section
| ISRCTN | ISRCTN62049497 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN62049497 |
| Secondary identifying numbers | N0436130343 |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 17/11/2010
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Pregnancy and Childbirth
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr S Saravanan
Scientific
Scientific
Obstetric Anaesthesia Office
Gledhow Wing
Leeds Teaching Hospitals NHS Trust
Beckett Street
Leeds
LS9 7TF
United Kingdom
| Phone | +44 (0)113 243 3144 |
|---|---|
| r&d@leedsth.nhs.uk |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | |
| Study objectives | The aim of this study is to determine whether ephedrine or phenylephrine or a combination provides the best prophylactic for prevention of hypotension after spinal anaesthesia |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Pregnancy and Childbirth: Anaesthesia |
| Intervention | Randomised controlled trial to determine whether ephedrine or phenylephrine or a combination provides the best prophylactic for prevention of hypotension after spinal anaesthesia. |
| Intervention type | Other |
| Primary outcome measure | Efficacy in preventing cardiovascular instability Uterine arterial blood gas analysis Incidence of nausea and vomiting under anaesthetic |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/01/2003 |
| Completion date | 01/07/2003 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Female |
| Target number of participants | Not provided at time of registration |
| Key inclusion criteria | Women who have completed 36 weeks of normal pregnancy, fit and well normally and who are planned to have an elective caesarean section under spinal anaesthesia will be recruited |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/01/2003 |
| Date of final enrolment | 01/07/2003 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Obstetric Anaesthesia Office
Leeds
LS9 7TF
United Kingdom
LS9 7TF
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.dh.gov.uk/Home/fs/en |
|---|
Funders
Funder type
Hospital/treatment centre
Leeds Teaching Hospitals NHS Trust
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/01/2006 | Yes | No |
