Stemming the Tide of Antibiotic Resistance: a trial of an intervention addressing the 'why' and 'how' of appropriate antibiotic prescribing in general practices
| ISRCTN | ISRCTN63355948 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN63355948 |
| Secondary identifying numbers | G0500956 |
- Submission date
- 26/06/2006
- Registration date
- 22/08/2006
- Last edited
- 22/05/2012
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Infections and Infestations
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Christopher Butler
Scientific
Scientific
Dept of General Practice
Cardiff University
3rd Floor Neuadd Merionnyd
Healh Park
Cardiff
CF14 4XN
United Kingdom
| butlercc@cf.ac.uk |
Study information
| Study design | Cluster-randomised trial with randomisation and analysis at the level of general practice/general practitioner. |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | GP practice |
| Study type | Treatment |
| Participant information sheet | Not available in web format, please use the contact details below to request a patient information sheet |
| Scientific title | |
| Study acronym | STAR |
| Study objectives | To examine if exposing prescribers in general practices to the STAR Educational Programme results in fewer antibiotics being dispensed to the practice's patients. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Infections |
| Intervention | Clinicians in practices randomised to the experimential condition will be exposed to the STAR Educational Program. This involves unique use of practices' own prescribing and resistance data and novel consulting strategies. Both the 'why' and 'how' of change will be addressed. Training methods will include: seminars, software supported, self-directed learning, and reflecting on video and actual consultations. Control practices will be offered the intervention after the initial one year follow-up of the experimental practices is complete. |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Oral Antibiotics |
| Primary outcome measure | Change in the total number of dispensed oral antibiotics (with examination of trend by quarter) per 1000 registered patients, for the year subsequent to the practice being exposed to the STAR programme, compared to the previous year, using PARC data. |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/06/2006 |
| Completion date | 30/11/2009 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | Up to 60 practices (approximately 140-180 clinicians) |
| Key inclusion criteria | There are no inclusion or exclusion criteria, other than that we aim for two thirds of prescribers in each practice must agree to take part in the study. Practices will be approached at random and randomised in a way that balances for practice size and prior antibiotic prescribing. |
| Key exclusion criteria | N/A |
| Date of first enrolment | 01/06/2006 |
| Date of final enrolment | 30/11/2009 |
Locations
Countries of recruitment
- United Kingdom
- Wales
Study participating centre
Dept of General Practice
Cardiff
CF14 4XN
United Kingdom
CF14 4XN
United Kingdom
Sponsor information
Cardiff University (UK)
University/education
University/education
Heath Park
Cardiff
CF14 4XN
Wales
United Kingdom
| davieskp2@cf.ac.uk | |
| Website | http://www.cardiff.ac.uk |
"ROR" |
https://ror.org/03kk7td41 |
Funders
Funder type
Research council
Medical Research Council (MRC)(ref. no: G0500956) (UK)
Government organisation / National government
Government organisation / National government
- Alternative name(s)
- Medical Research Council (United Kingdom), UK Medical Research Council, MRC
- Location
- United Kingdom
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 07/05/2010 | Yes | No | |
| Results article | results | 02/02/2012 | Yes | No |
