Contact information
Type
Scientific
Primary contact
Dr Hareld M.C. Kemps
ORCID ID
Contact details
Máxima Medical Centre
Department of Sport Medicine
P.O. Box 7777
Veldhoven
5500 MB
Netherlands
+31 (0)40 8888620
H.Kemps@wxs.nl
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N/A
Study information
Scientific title
Acronym
Study hypothesis
The time constant of oxygen uptake during recovery of submaximal exercise is a reliable parameter to measure the effects of exercise training in patients with chronic heart failure
Ethics approval
Not provided at time of registration
Study design
Randomised crossover study
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Treatment
Patient information sheet
Condition
Heart failure
Intervention
Exercise training (12 weeks) versus standard care
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
Change of time constant of oxygen onset or recovery kinetics >10 seconds
Secondary outcome measures
1. Change in peak volume of oxygen (VO2)
2. Quality of life
Overall trial start date
01/09/2002
Overall trial end date
01/01/2007
Reason abandoned
Eligibility
Participant inclusion criteria
Stable chronic heart failure (CHF) (New York Heart Association [NYHA] class II-III and echocardiographical ejection fraction </= 40%) attributed to idiopathic dilated cardiomyopathy or ischemic heart disease due to myocardial infarction
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
40
Participant exclusion criteria
1. Myocardial infarction or unstable angina pectoris in previous three months
2. Atrial fbrillation or flutter
3. Chronic obstructive pulmonary disorder (COPD) (Tiffenau index <60%)
Recruitment start date
01/09/2002
Recruitment end date
01/01/2007
Locations
Countries of recruitment
Netherlands
Trial participating centre
Máxima Medical Centre
Veldhoven
5500 MB
Netherlands
Funders
Funder type
Charity
Funder name
'Friends of the Heart' Foundation (Stichting 'Vrienden van het Hart')
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary