Effects of exercise training on oxygen onset and recovery kinetics at submaximal exercise in patients with chronic heart failure
| ISRCTN | ISRCTN66318889 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN66318889 |
| Secondary identifying numbers | NL576, NTR632 |
- Submission date
- 19/07/2006
- Registration date
- 19/07/2006
- Last edited
- 08/01/2021
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Hareld M.C. Kemps
Scientific
Scientific
Máxima Medical Centre
Department of Sport Medicine
P.O. Box 7777
Veldhoven
5500 MB
Netherlands
| Phone | +31 (0)40 8888620 |
|---|---|
| H.Kemps@wxs.nl |
Study information
| Study design | Randomised crossover study |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Treatment |
| Scientific title | Effects of exercise training on oxygen onset and recovery kinetics at submaximal exercise in patients with chronic heart failure |
| Study objectives | The time constant of oxygen uptake during recovery of submaximal exercise is a reliable parameter to measure the effects of exercise training in patients with chronic heart failure |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Heart failure |
| Intervention | Exercise training (12 weeks) versus standard care |
| Intervention type | Other |
| Primary outcome measure | Change of time constant of oxygen onset or recovery kinetics >10 seconds |
| Secondary outcome measures | 1. Change in peak volume of oxygen (VO2) 2. Quality of life |
| Overall study start date | 01/09/2002 |
| Completion date | 01/01/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | 40 |
| Total final enrolment | 24 |
| Key inclusion criteria | Stable chronic heart failure (CHF) (New York Heart Association [NYHA] class II-III and echocardiographical ejection fraction </= 40%) attributed to idiopathic dilated cardiomyopathy or ischemic heart disease due to myocardial infarction |
| Key exclusion criteria | 1. Myocardial infarction or unstable angina pectoris in previous three months 2. Atrial fbrillation or flutter 3. Chronic obstructive pulmonary disorder (COPD) (Tiffenau index <60%) |
| Date of first enrolment | 01/09/2002 |
| Date of final enrolment | 01/01/2007 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
Máxima Medical Centre
Veldhoven
5500 MB
Netherlands
5500 MB
Netherlands
Sponsor information
Máxima Medical Center, Department of Sport Medicine (The Netherlands)
Hospital/treatment centre
Hospital/treatment centre
P.O. Box 7777
Veldhoven
5500 MB
Netherlands
"ROR" |
https://ror.org/02x6rcb77 |
|---|
Funders
Funder type
Charity
'Friends of the Heart' Foundation (Stichting 'Vrienden van het Hart')
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Abstract results | results presented at the European Society of Cardiology meeting | 01/05/2006 | 08/01/2021 | No | No |
Editorial Notes
08/01/2021: The following changes have been made:
1. Publication reference added.
2. The final enrolment number has been added from the reference.
3. The NTR numbers have been added.
