High intensity exercise may be an efficient startegy for obesity management
| ISRCTN | ISRCTN66508384 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN66508384 |
| Secondary identifying numbers | N/A |
- Submission date
- 26/02/2016
- Registration date
- 01/03/2016
- Last edited
- 30/11/2020
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Nutritional, Metabolic, Endocrine
Plain English summary of protocol
Background and study aims
Sedentary behaviour (taking part in less than an hour a week of physical activity) is associated with an increased risk of heart disease, type 2 diabetes and some forms of cancer, as well as poorer mental wellbeing. It is a growing problem, and is thought to contribute significantly to the high levels of obesity worldwide. For many people, not having enough time to exercise is often used as an excuse for sedentary behaviour. There is therefore a growing amount of research looking into exercise strategies that involve a shorter time commitment but still provide health benefits. A recent study showed that very brief high-intensity exercise in the form of sprinting, made up of sprints lasting for 6-10 seconds, was found to be motivating and tolerable for participants and can even help to burn fat. The aim of this study is to find out whether taking part in high intensity exercise for six weeks can help improve blood sugar control, BMI and physical fitness in young obese adults.
Who can participate?
Obese adults aged between 18 and 30 who have a sedentary lifestyle.
What does the study involve?
Participants are randomly allocated to one of two groups. Those in the first group take part in the training program, which consists of three training sessions per week for six weeks (a total of 18). Those in the second group do not take part in any training during the 6 weeks and are also asked to consume their normal diet and to maintain their typically sedentary behavior during the training period. At the start of the study, after the program ends and then 24, 72 hours and two weeks after the final session, participants in both groups complete a number of tests in order to assess how well their bodies are able to process sugar, physical characteristics (such as weight) and how physically fit they are.
What are the possible benefits and risks of participating?
Participants will benefit from being informed about their health and fitness levels and could also take advantage of training program to improve their physical fitness and health. There are no direct risks to participants taking part in this study.
Where is the study run from?
University of Moncton (Canada)
When is the study starting and how long is it expected to run for?
January 2014 to June 2014
Who is funding the study?
University of Moncton (Canada)
Who is the main contact?
Dr Jabbour Georges
georges.jabbour@umoncton.ca
Contact information
Scientific
School of Kinesiology and Leisure
Faculty of Health Sciences and Community Services
Université de Moncton
Moncton
E1A 3E9
Canada
| Phone | +1 506 858 3757 |
|---|---|
| georges.jabbour@umoncton.ca |
Study information
| Study design | Single-center randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Other |
| Study type | Treatment |
| Participant information sheet | Not available in web format, please use the contact details below to request a patient information sheet. |
| Scientific title | Effect of supramaximal exercise training on performance variables and metabolic changes in obese adults |
| Study objectives | The aim of this study is to evaluate the effects of six weeks of supramaximal exercise training (SET) and determine its effects on blood glucose control and insulin resistance, BMI and fitness. |
| Ethics approval(s) | University’s Human Research Ethics Committee (UHRC) of the University of Moncton, 03/12/2013, ref: 1314-020 |
| Health condition(s) or problem(s) studied | Obesity |
| Intervention | At the start of the study, participants undergo two sessions of preliminary testing after an overnight fast to determine athropometric measurements, phsyiological measures (lung capacity and blood pressure) and metabolic testing. Once the participants completed preliminary testing, they complete a total of 18 training sessions (three sessions per week for six weeks). Each of the prescribed sessions begins with a 5-minute warm-up of continuous cycling at moderate intensity (40% of their individual VO2peak power) followed by 6 repetitions of SET intervals with 2 minutes of passive recovery between each repetition. Each SET repetition lasts for six seconds, and the participants are asked to pedal at maximal velocity against the resistance determined during day three. The total duration of each session is approximately 15 minutes. The training sessions are conducted under the supervision of a member of the research team, and velocities (in RPM) were recorded for each second of the bout to ensure that fixed velocities remained constant. Post-intervention metabolic and blood pressure measurements are conducted 24-hours, 72-hours and two-weeks after the final training session to obtain information on the potential lasting effects of SET. The post-intervention anthropometric assessment is performed 24 hours after the final SET session, and the post-intervention exercise tests are performed 72 hours after the final SET session. |
| Intervention type | Other |
| Primary outcome measure | Insulin resistance (HOMA-IR) is determined by measuring blood glucose and insulin concentrations at baseline, 24 hours, 72 hours and 2 weeks post-intervention. |
| Secondary outcome measures | 1. BMI is calculated as the ratio of mass (kg) to height squared (m2) at baseline and 24 hours post-intervention 2. Maximal oxygen consumption (VO2max) is measured using an incremental maximal test at baseline and 72 hours post-intervention 3. Maximal power is measured using a force-velocity test on a cycle ergometer at baseline and 72 hours post-intervention 4. Blood pressure is measured using an automated blood pressure monitor at baseline, 72 hours and 2 weeks post-intervention |
| Overall study start date | 10/01/2014 |
| Completion date | 01/06/2014 |
Eligibility
| Participant type(s) | Healthy volunteer |
|---|---|
| Age group | Adult |
| Lower age limit | 18 Years |
| Sex | Both |
| Target number of participants | 24 |
| Total final enrolment | 24 |
| Key inclusion criteria | 1. Aged between 18 an 30 years 2. Obesity (BMI >30 kg/m2) 3. Sedentary (<1 h/week of structured exercise) |
| Key exclusion criteria | History of cardiovascular or chronic health problems, drug consumption, or smoking. |
| Date of first enrolment | 01/02/2014 |
| Date of final enrolment | 25/02/2014 |
Locations
Countries of recruitment
- Canada
Study participating centre
Faculty of Health Sciences and Community Services
Moncton
E1A 3E9
Canada
Sponsor information
University/education
Faculty of Superior Studies and Research
Campus de Moncton
Pavillon Léopold-Taillon
18, avenue Antonine-Maillet
Moncton
E1A 3E9
Canada
"ROR" |
https://ror.org/029tnqt29 |
|---|
Funders
Funder type
University/education
No information available
Results and Publications
| Intention to publish date | 31/12/2016 |
|---|---|
| Individual participant data (IPD) Intention to share | Yes |
| IPD sharing plan summary | Available on request |
| Publication and dissemination plan | Planned publication of a study protocol and results paper in an international peer-reviewed scientific journal. |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 28/09/2017 | 30/11/2020 | Yes | No |
Editorial Notes
30/11/2020: Publication reference and total final enrolment added.
