Condition category
Mental and Behavioural Disorders
Date applied
14/02/2006
Date assigned
14/02/2006
Last edited
17/08/2009
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr A.M. Pot

ORCID ID

Contact details

Trimbos-institute
Netherlands Institute of Mental Health and Addiction
P.O. Box 725
Utrecht
3500 AS
Netherlands
ampot@trimbos.nl

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

NTR541

Study information

Scientific title

Acronym

Study hypothesis

Looking for meaning leads to a significant reduction of depressive symptoms and a significant enhancement of wellbeing, meaning in life and quality of life with elderly with depressive symptoms in comparison to a no treatment control group.

Ethics approval

Received from local medical ethics committee

Study design

Multicentre randomised single blind active controlled parallel group trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Other

Trial type

Quality of life

Patient information sheet

Condition

Depressive symptoms

Intervention

The course looking for meaning is the intervention. It is a group-oriented intervention of twelve sessions of two hours, conducted in groups of about ten participants. Based on certain themes, in this intervention participants are invited to take memories from their own lives. The special thing about the course is that reminiscence is linked to creative assignments. Imagination and creativity are viewed as important keys to perceived meaning, competencies and well-being. Via targeted questions, participants evaluate and re-evaluate their own lives.

The control group receive no treatment.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

1. Depressive symptoms (Centre of Epidemiological Studies-Depression scale [CES-D], Bouma, Ranchor, Sanderman and van Sonderen 1995)
2. Well-being (Well-being Scale, Ryff and Keyes, 1995)
3. Perceived meaning (SELE Scale, Dittmann-Kohli and Westerhof 1997)
4. Quality of life (EuroQol Group 1990)

Secondary outcome measures

1. Mastery (Pearlin Mastery Scale, Pearlin and Schooler 1978)
2. Social support (van Sonderen et al. 1989)
3. Personality structure (NEO-FFI)
4. Demographic variables and important life events

Overall trial start date

01/11/2005

Overall trial end date

01/11/2007

Reason abandoned

Eligibility

Participant inclusion criteria

Elderly people above the age of 55 with slight to moderate depressive symptoms.

Participant type

Patient

Age group

Senior

Gender

Both

Target number of participants

360

Participant exclusion criteria

1. People with severe depressive symptoms and a CES-D score higher than 24
2. The absence of depressive symptoms, a score lower than 5 on the CES-D
3. People being treated elsewhere (with medication) when they register
4. People unable to function in a group

Recruitment start date

01/11/2005

Recruitment end date

01/11/2007

Locations

Countries of recruitment

Netherlands

Trial participating centre

Trimbos-institute
Utrecht
3500 AS
Netherlands

Sponsor information

Organisation

Trimbos Institute - Netherlands Institute of Mental Health and Addiction (Netherlands)

Sponsor details

P.O. Box 725
Utrecht
3500 AS
Netherlands
+31 (0)30 2971100
info@trimbos.nl

Sponsor type

Research organisation

Website

Funders

Funder type

Research organisation

Funder name

Netherlands Organisation for Health Research and Development (ZonMw) (Netherlands)

Alternative name(s)

Netherlands Organisation for Health Research and Development

Funding Body Type

private sector organisation

Funding Body Subtype

other non-profit

Location

Netherlands

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2008 results in http://www.ncbi.nlm.nih.gov/pubmed/18554393

Publication citations

  1. Results

    Pot AM, Melenhorst AS, Onrust S, Bohlmeijer ET, (Cost)effectiveness of life review for older adults: design of a randomized controlled trial., BMC Public Health, 2008, 8, 211, doi: 10.1186/1471-2458-8-211.

Additional files

Editorial Notes