Condition category
Mental and Behavioural Disorders
Date applied
23/10/2000
Date assigned
23/10/2000
Last edited
24/11/2010
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr J Orford

ORCID ID

Contact details

School of Psychology
University of Birmingham
Edgbaston
Birmingham
B15 2TT
United Kingdom
+44 (0)121 414 4918
j.f.orford@bham.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

G9700729

Study information

Scientific title

Acronym

UKATT

Study hypothesis

1. To conduct a multi-centre trial of treatment for alcohol problems within the context of the UK treatment system
2. To examine outcomes from a socially based treatment which both theory and research suggest may be effective and cost-effective compared with MET
3. To enquire what types of patient are suited to MET and what types of patient do not benefit from MET and may therefore need a more intensive form of treatment.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Neuroscience, psychiatry

Intervention

Motivational Enhancement Therapy (MET)
Social Behaviour Network Therapy (SBNT)

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Categorical outcome of treatment plus continuous change in levels of:
1. Alcohol consumption
2. Gamma-glutamyl transferase (GGT)
3. Alcohol dependence
4. Alcohol-related problems

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/04/1998

Overall trial end date

31/10/2002

Reason abandoned

Eligibility

Participant inclusion criteria

A Diagnostic and Statistical Manual of Mental Disorders - Fourth Edition (DSM-IV) diagnosis of alcohol abuse or alcohol dependence

Participant type

Patient

Age group

Adult

Gender

Not Specified

Target number of participants

720

Participant exclusion criteria

1. Less than 16 years old
2. Abstinence from drinking during 3 months prior to screening
3. Currently receiving another form of alcohol treatment;
4. Intending to seek another form of alcohol treatment within 3 months
5. Other drug use the main problem area
6. Recommended by their clinician for treatment for their other drug use
7. Unable to provide a trace contact
8. Has an uncontrolled mental illness preventing treatment compliance
9. Has a severe language or cognitive problem
10. Has previously been entered into UKATT
11. Is a significant other or network member of an existing UKATT client;
12. Will definitely be moving to another area within 15 months

Recruitment start date

01/04/1998

Recruitment end date

31/10/2002

Locations

Countries of recruitment

United Kingdom

Trial participating centre

School of Psychology
Birmingham
B15 2TT
United Kingdom

Sponsor information

Organisation

Medical Research Council (MRC) (UK)

Sponsor details

20 Park Crescent
London
W1B 1AL
United Kingdom
+44 20 7636 5422
clinical.trial@headoffice.mrc.ac.uk

Sponsor type

Research council

Website

http://www.mrc.ac.uk

Funders

Funder type

Research council

Funder name

Medical Research Council (UK)

Alternative name(s)

MRC

Funding Body Type

private sector organisation

Funding Body Subtype

other non-profit

Location

United Kingdom

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

1. 2001 protocol in http://www.ncbi.nlm.nih.gov/pubmed/11139410
2. 2005 results in http://www.ncbi.nlm.nih.gov/pubmed/16150764
3. 2006 results in http://www.ncbi.nlm.nih.gov/pubmed/16393192

Publication citations

  1. Protocol

    United Kingdom Alcohol Treatment Trial (UKATT): hypotheses, design and methods., Alcohol Alcohol., 36, 1, 11-21.

  2. Results

    Effectiveness of treatment for alcohol problems: findings of the randomised UK alcohol treatment trial (UKATT)., BMJ, 2005, 331, 7516, 541, doi: 10.1136/bmj.331.7516.541.

  3. Results

    Orford J, Hodgson R, Copello A, John B, Smith M, Black R, Fryer K, Handforth L, Alwyn T, Kerr C, Thistlethwaite G, Slegg G, , The clients' perspective on change during treatment for an alcohol problem: qualitative analysis of follow-up interviews in the UK Alcohol Treatment Trial., Addiction, 2006, 101, 1, 60-68, doi: 10.1111/j.1360-0443.2005.01291.x.

Additional files

Editorial Notes