Contact information
Type
Scientific
Primary contact
Dr J Orford
ORCID ID
Contact details
School of Psychology
University of Birmingham
Edgbaston
Birmingham
B15 2TT
United Kingdom
+44 (0)121 414 4918
j.f.orford@bham.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
G9700729
Study information
Scientific title
Acronym
UKATT
Study hypothesis
1. To conduct a multi-centre trial of treatment for alcohol problems within the context of the UK treatment system
2. To examine outcomes from a socially based treatment which both theory and research suggest may be effective and cost-effective compared with MET
3. To enquire what types of patient are suited to MET and what types of patient do not benefit from MET and may therefore need a more intensive form of treatment.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Neuroscience, psychiatry
Intervention
Motivational Enhancement Therapy (MET)
Social Behaviour Network Therapy (SBNT)
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
Categorical outcome of treatment plus continuous change in levels of:
1. Alcohol consumption
2. Gamma-glutamyl transferase (GGT)
3. Alcohol dependence
4. Alcohol-related problems
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/04/1998
Overall trial end date
31/10/2002
Reason abandoned
Eligibility
Participant inclusion criteria
A Diagnostic and Statistical Manual of Mental Disorders - Fourth Edition (DSM-IV) diagnosis of alcohol abuse or alcohol dependence
Participant type
Patient
Age group
Adult
Gender
Not Specified
Target number of participants
720
Participant exclusion criteria
1. Less than 16 years old
2. Abstinence from drinking during 3 months prior to screening
3. Currently receiving another form of alcohol treatment;
4. Intending to seek another form of alcohol treatment within 3 months
5. Other drug use the main problem area
6. Recommended by their clinician for treatment for their other drug use
7. Unable to provide a trace contact
8. Has an uncontrolled mental illness preventing treatment compliance
9. Has a severe language or cognitive problem
10. Has previously been entered into UKATT
11. Is a significant other or network member of an existing UKATT client;
12. Will definitely be moving to another area within 15 months
Recruitment start date
01/04/1998
Recruitment end date
31/10/2002
Locations
Countries of recruitment
United Kingdom
Trial participating centre
School of Psychology
Birmingham
B15 2TT
United Kingdom
Sponsor information
Organisation
Medical Research Council (MRC) (UK)
Sponsor details
20 Park Crescent
London
W1B 1AL
United Kingdom
+44 (0)20 7636 5422
clinical.trial@headoffice.mrc.ac.uk
Sponsor type
Research council
Website
Funders
Funder type
Research council
Funder name
Medical Research Council (UK)
Alternative name(s)
MRC
Funding Body Type
government organisation
Funding Body Subtype
Federal/National Government
Location
United Kingdom
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
1. 2001 protocol in http://www.ncbi.nlm.nih.gov/pubmed/11139410
2. 2005 results in http://www.ncbi.nlm.nih.gov/pubmed/16150764
3. 2006 results in http://www.ncbi.nlm.nih.gov/pubmed/16393192
Publication citations
-
Protocol
United Kingdom Alcohol Treatment Trial (UKATT): hypotheses, design and methods., Alcohol Alcohol., 36, 1, 11-21.
-
Results
Effectiveness of treatment for alcohol problems: findings of the randomised UK alcohol treatment trial (UKATT)., BMJ, 2005, 331, 7516, 541, doi: 10.1136/bmj.331.7516.541.
-
Results
Orford J, Hodgson R, Copello A, John B, Smith M, Black R, Fryer K, Handforth L, Alwyn T, Kerr C, Thistlethwaite G, Slegg G, , The clients' perspective on change during treatment for an alcohol problem: qualitative analysis of follow-up interviews in the UK Alcohol Treatment Trial., Addiction, 2006, 101, 1, 60-68, doi: 10.1111/j.1360-0443.2005.01291.x.