Condition category
Not Applicable
Date applied
08/07/2008
Date assigned
08/08/2008
Last edited
11/07/2014
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Prof Gunther Eysenbach

ORCID ID

Contact details

190 Elizabeth St
Toronto
M5G 2C4
Canada

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

MOP-84476

Study information

Scientific title

Acronym

Study hypothesis

New public policies in the United States of America (USA), Canada, and other countries stipulate that publicly funded research must be made publicly accessible, for example by depositing it in subject repositories such as PubMed Central or in institutional repositories. It is unclear if this results in higher visibility and higher number of citations. We will investigate whether manuscripts which are accessible through PubMed Central (PMC) or other repositories receive a higher citation count than manuscripts which are not made accessible through "self-archiving" (i.e., depositing manuscripts in subject
repositories).

Ethics approval

Ethics approval pending from the University Health Network Research Ethics Board (UHN REB) as of 10/07/2008. Application submitted on 07/07/2008.

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Other

Patient information sheet

Not available in web format, please use the contact details below to request a patient information sheet

Condition

Medical publishing

Intervention

The unit to be randomised are published manuscripts. The authors will be sending their manuscripts to be randomised so that the authors will not know whether the manuscript will be either archived on Pubmed Central (intervention) or not (control). A citation analysis will be performed every 6 months for a minimum of 3 years.

Subset analyses.
The data analysis plan involves comparing the mean number of citations as well as the proportion of uncited manuscripts between the control and intervention group every 6 months. We are also planning three separate subset analyses:
1. We will compare the two groups within discipline-specific subgroups
2. We will compare the two groups in subgroups depending on the timing of open access (e.g. a subgroup of only those articles which are immediately open access, or within a subgroup of manuscripts which are open access after 12 months)
3. We will compare the groups in subgroups of highly cited and less cited manuscripts at baseline

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Citations within the scientific literature, assessed every 6 months.

Secondary outcome measures

Other measurements for uptake and dissemination of scientific knowledge, including:
1. Citations in news articles
2. Citations on the Internet
3. Uptake by end-users and policy makers

Assessed every 6 months.

Overall trial start date

01/08/2008

Overall trial end date

01/08/2013

Reason abandoned

Eligibility

Participant inclusion criteria

1. Authors of manuscripts with at least one NIH-funded co-author
2. Manuscript published between January 1st 2008 and April 7th 2008
3. Manuscript is not already accessible on PMC or as free full text elsewhere
4. The copyright policies of the journal allow 'self-archiving' on subject repositories such as PMC

Participant type

Patient

Age group

Other

Gender

Both

Target number of participants

500 authors to be contacted, expected participation rate approx 40% (target sample size: 200 manuscripts)

Participant exclusion criteria

1. Authors whose email address is not listed in the affiliation field of PubMed
2. Letters, editorials, and reviews

Recruitment start date

01/08/2008

Recruitment end date

01/08/2013

Locations

Countries of recruitment

Canada

Trial participating centre

190 Elizabeth St
Toronto
M5G 2C4
Canada

Sponsor information

Organisation

University Health Network (Canada)

Sponsor details

Centre for Global eHealth Innovation
R. Fraser Elliott Building
4th Floor
room # 4S435
190 Elizabeth Street
Toronto
M5G 2C4
Canada

Sponsor type

University/education

Website

http://www.uhn.ca/index.htm

Funders

Funder type

Research organisation

Funder name

Canadian Institutes of Health Research (Canada), ref: MOP-84476

Alternative name(s)

Instituts de Recherche en Santé du Canada, CIHR

Funding Body Type

government organisation

Funding Body Subtype

Federal/National Government

Location

Canada

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes