Chronic effect of exercise on attention and working memory in children

ISRCTN	ISRCTN70853932
DOI	https://doi.org/10.1186/ISRCTN70853932
Secondary identifying numbers	N/A

Submission date: 20/06/2006
Registration date: 04/07/2007
Last edited: 06/01/2021

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Nutritional, Metabolic, Endocrine

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof John Reilly
Scientific

Division of Developmental Medicine
University of Glasgow
1st Floor Tower Block, QMH
Yorkhill Hospitals
Dalnair Street
Glasgow
G3 8SJ
United Kingdom

Email	jjr2y@clinmed.gla.ac.uk

Study information

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Treatment
Scientific title	Chronic effect of exercise on attention and working memory in children
Study acronym	LEAPFROG - CHRONIC
Study objectives	There is increasing concern that modern children lead very sedentary lives. An inactive lifestyle increases risks of obesity and metabolic disease, but may also have adverse effects on cognitive function. Two recent systematic reviews/meta-analyses have concluded that there is a need for a Randomised Controlled Trial (RCT) to test the hypothesis that exercise can affect cognition in children, and to determine dose-response relationships. The aim of this study is: 1. To test the hypothesis that chronic aerobic exercise has effects on attention and working memory in children 2. To pilot for a larger scale future RCT
Ethics approval(s)	Received from Yorkhill Hospitals Glasgow LREC (ref.: 05/s0708/89).
Health condition(s) or problem(s) studied	Obesity
Intervention	Intervention group: Aerobic exercise sessions for approximately 90 minutes per week delivered as physical education. Control group: Flexibility strength skill development for approximately 90 minutes per week, delivered as physical education.
Intervention type	Other
Primary outcome measure	Executive function measured by: 1. Cognitive Assessment System (CAS) 2. Attentional Network Task (ANT) 3. Cambridge Neuropsychological Test Battery (CANTAB)
Secondary outcome measures	Conners Attention Deficit Hyperactivity Disorder (ADHD) Index.
Overall study start date	01/06/2006
Completion date	01/08/2007

Eligibility

Participant type(s)	Patient
Age group	Child
Lower age limit	6 Years
Upper age limit	8 Years
Sex	Both
Target number of participants	60 to 80 (30 to 40 in each group)
Total final enrolment	64
Key inclusion criteria	Healthy children age 6 - 8 years attending mainstream primary schools.
Key exclusion criteria	Diagnosis of any disorder of attention or memory.
Date of first enrolment	01/06/2006
Date of final enrolment	01/08/2007

Locations

Countries of recruitment

Scotland
United Kingdom

Study participating centre

Division of Developmental Medicine

Glasgow
G3 8SJ
United Kingdom

Sponsor information

Yorkhills Hospitals NHS Trust (UK)
Hospital/treatment centre

Dr Alison Wood
R & D Office, Harley Street
Royal Hospital for Sick Children
Yorkhill Hospitals
Dalnair Street
Glasgow
G3 8SJ
Scotland
United Kingdom

Website	http://www.nhsggc.org.uk/

Funders

Funder type

Government

Scottish Executive Health Department (UK)

No information available

Chief Scientist's Office (UK)

No information available

Yorkhill Children's Foundation Studentship (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	28/10/2011		Yes	No

Editorial Notes

06/01/2021: Total final enrolment added.