Condition category
Urological and Genital Diseases
Date applied
29/09/2006
Date assigned
29/09/2006
Last edited
13/10/2011
Prospective/Retrospective
Retrospectively registered
Overall trial status
Stopped
Recruitment status
Stopped

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Prof M M Yaqoob

ORCID ID

Contact details

Renal Unit
Basement West Wing
The Royal London Hospital
Whitechapel
London
E1 1BB
United Kingdom
+44 020 7377 7480
m.m.yaqoob@qmul.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0205164619

Study information

Scientific title

Acronym

Study hypothesis

1. In patients undergoing dialysis, do calcimimetics reduce calcium deposition in the arteries and thereby reduce risk of cardiovascular events?
2. Is medical parathyroidectomy superior to surgical parathyroidectomy in reducing cardiovascular risks and improving abnormalities of mineral metabolism?

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Urological and Genital Diseases: Renal

Intervention

Calcimimetics vs surgical parathyroidectomy.

Added June 2008: the trial was stopped due to poor recruitment.

Intervention type

Drug

Phase

Not Specified

Drug names

calcimimetics

Primary outcome measures

Progression of disease as determined by multislice CT coronary calcium scores, Dexa scans pulse wave velocity, and carotid intima media thickness.

Secondary outcome measures

Not provided at time of registration

Overall trial start date

28/03/2005

Overall trial end date

30/09/2007

Reason abandoned

Poor recruitment

Eligibility

Participant inclusion criteria

Not provided at time of registration

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

50

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

28/03/2005

Recruitment end date

30/09/2007

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Renal Unit
London
E1 1BB
United Kingdom

Sponsor information

Organisation

Record Provided by the NHSTCT Register - 2006 Update - Department of Health

Sponsor details

The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
+44 (0)20 7307 2622
dhmail@doh.gsi.org.uk

Sponsor type

Government

Website

http://www.dh.gov.uk/Home/fs/en

Funders

Funder type

Government

Funder name

Barts and The London NHS Trust (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Queen Mary University of London - QMUL

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

NHS R&D Support Funding

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes