Contact information
Type
Scientific
Primary contact
Prof Tom Craig
ORCID ID
Contact details
Institute Of Psychiatry
16 De Crespigny Park
London
SE5 8AF
United Kingdom
t.craig@iop.kcl.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
6104
Study information
Scientific title
Enhancing delivery and outcomes of vocational rehabilitation (ENDEAVOR): improving outcomes for young people with a first episode psychosis
Acronym
ENDEAVOR
Study hypothesis
Primary hypothesis:
To compare the effectiveness of two vocational rehabilitation interventions in helping people attain and retain employment following a first episode of psychosis.
Secondary hypothesis:
To describe the pathways,barriers and facillitators to employment in a cohort of people suffering a first episode psychosis.
Ethics approval
Charing Cross Research Ethics Committee approved on the 15th December 2008 (ref: 08/H0711/136)
Study design
Multicentre randomised interventional treatment trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Condition
Topic: Mental Health Research Network; Subtopic: Psychosis; Disease: Schizophrenia
Intervention
1. Supported employment
2. Return to employment/eduation after first episode psychosis
Study entry: single randomisation only
Intervention type
Other
Phase
Not Applicable
Drug names
Primary outcome measure
Employment status, measured at 12 months
Secondary outcome measures
Measured at 12 months:
1. Employment and education/training across follow up; qualifications obtained
2. Positive and Negative Symptom Scale (PANSS)
3. Global Assessment of Function
4. Time Budget
5. Client Service Receipt Inventory
Overall trial start date
01/06/2009
Overall trial end date
30/09/2011
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
1. First episode psychosis
2. Aged 18 - 35 years, either sex
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
Planned sample size: 200; UK sample size: 200
Participant exclusion criteria
1. Organic disease
2. Unable to comprehend written English
3. Unable to give informed consent
Recruitment start date
01/06/2009
Recruitment end date
30/09/2011
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Institute Of Psychiatry
London
SE5 8AF
United Kingdom
Sponsor information
Organisation
Kings College London (KCL) (UK)
Sponsor details
Institute of Psychiatry
Department of Psychology
Henry Wellcome Building
Box PO77
16 De Crespigny Park
London
SE5 8AF
United Kingdom
Sponsor type
University/education
Website
Funders
Funder type
Government
Funder name
National Institute for Health Research (NIHR) (UK) - Research for Patient Benefit (RfPB) programme
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/24855129
Publication citations
-
Results
Craig T, Shepherd G, Rinaldi M, Smith J, Carr S, Preston F, Singh S, Vocational rehabilitation in early psychosis: cluster randomised trial., Br J Psychiatry, 2014, doi: 10.1192/bjp.bp.113.136283.