Condition category
Mental and Behavioural Disorders
Date applied
18/06/2010
Date assigned
18/06/2010
Last edited
27/05/2014
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Prof Tom Craig

ORCID ID

Contact details

Institute Of Psychiatry
16 De Crespigny Park
London
SE5 8AF
United Kingdom
t.craig@iop.kcl.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

6104

Study information

Scientific title

Enhancing delivery and outcomes of vocational rehabilitation (ENDEAVOR): improving outcomes for young people with a first episode psychosis

Acronym

ENDEAVOR

Study hypothesis

Primary hypothesis:
To compare the effectiveness of two vocational rehabilitation interventions in helping people attain and retain employment following a first episode of psychosis.

Secondary hypothesis:
To describe the pathways,barriers and facillitators to employment in a cohort of people suffering a first episode psychosis.

Ethics approval

Charing Cross Research Ethics Committee approved on the 15th December 2008 (ref: 08/H0711/136)

Study design

Multicentre randomised interventional treatment trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Not available in web format, please use the contact details below to request a patient information sheet

Condition

Topic: Mental Health Research Network; Subtopic: Psychosis; Disease: Schizophrenia

Intervention

1. Supported employment
2. Return to employment/eduation after first episode psychosis

Study entry: single randomisation only

Intervention type

Other

Phase

Not Applicable

Drug names

Primary outcome measures

Employment status, measured at 12 months

Secondary outcome measures

Measured at 12 months:
1. Employment and education/training across follow up; qualifications obtained
2. Positive and Negative Symptom Scale (PANSS)
3. Global Assessment of Function
4. Time Budget
5. Client Service Receipt Inventory

Overall trial start date

01/06/2009

Overall trial end date

30/09/2011

Reason abandoned

Eligibility

Participant inclusion criteria

1. First episode psychosis
2. Aged 18 - 35 years, either sex

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

Planned sample size: 200; UK sample size: 200

Participant exclusion criteria

1. Organic disease
2. Unable to comprehend written English
3. Unable to give informed consent

Recruitment start date

01/06/2009

Recruitment end date

30/09/2011

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Institute Of Psychiatry
London
SE5 8AF
United Kingdom

Sponsor information

Organisation

Kings College London (KCL) (UK)

Sponsor details

Institute of Psychiatry
Department of Psychology
Henry Wellcome Building
Box PO77
16 De Crespigny Park
London
SE5 8AF
United Kingdom

Sponsor type

University/education

Website

http://www.iop.kcl.ac.uk/

Funders

Funder type

Government

Funder name

National Institute for Health Research (NIHR) (UK) - Research for Patient Benefit (RfPB) programme

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/24855129

Publication citations

  1. Results

    Craig T, Shepherd G, Rinaldi M, Smith J, Carr S, Preston F, Singh S, Vocational rehabilitation in early psychosis: cluster randomised trial., Br J Psychiatry, 2014, doi: 10.1192/bjp.bp.113.136283.

Additional files

Editorial Notes