Condition category
Mental and Behavioural Disorders
Date applied
11/05/2011
Date assigned
26/05/2011
Last edited
27/11/2015
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Background and study aims
Taste plays an important role in what we decide to eat or drink. It is also thought that different types of taste, such as sweet or savoury, can influence our appetite and the amount we actually eat. Studies have shown that sweet-tasting foods can increase the appetite, and so we are likely to eat more. There have been very few studies testing the effects of savoury-tasting foods on appetite however. The aim of this study is to compare the effects of sweet and savoury pre-loads (flavoured drinks before meals) on feelings of hunger and food intake.

Who can participate?
Health women between the ages of 18 and 30.

What does the study involve?
Participants are randomly allocated to one of three groups. Those in the first group are given a sweet-tasting milk-based drink, flavoured with chocolate and sweetened with sucrose (sugar). Those in the second group are given a savoury-tasting milk-based drink flavoured with mushroom and monosodium glutamate (MSG). Those in the third group are given a bland-tasting milk-based drink containing powdered skimmed milk and corn flour. Participants in all three groups are then given a very large portion of food (including both sweet and savoury tastes) and told to eat as much as they like. The amount of food the participants in each group eat is then recorded. This exercise is repeated every day for four days. Throughout the 4 days, participants are interviewed to find out how full they are feeling before and after the meals.

What are the possible benefits and risks of participating?
Not provided at time of registration.

Where is the study run from?
Institute of Psychological Sciences, Leeds (UK)

When is the study starting and how long is it expected to run for?
March 2008 to August 2008

Who is funding the study?
1. Ajinomoto Inc. (Japan)
2. Biotechnology and Biological Sciences Research Council (UK)
3. European Union (Belgium)

Who is the main contact?
Dr Graham Finayson

Trial website

Contact information

Type

Scientific

Primary contact

Dr Graham Finlayson

ORCID ID

Contact details

Institute of Psychological Sciences
University of Leeds
Leeds
LS2 9JT
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

08073-01

Study information

Scientific title

Influence of savoury or sweet food on sensory regulation of appetite and liking and wanting for foods: a single centre cross-sectional randomised cross-over study

Acronym

TasteSat

Study hypothesis

1. Savoury taste will have a stronger modulating effect on food preference than sweet or bland taste
2. Individual differences in psychological eating behaviour traits will moderate the effect of taste on satiety and food preference

Ethics approval

Institution of Psychological Sciences Ethics Committe, University of Leeds, 11th March 2008, Ref: 08073-01

Study design

Single centre cross-sectional randomised crossover study

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Other

Trial type

Screening

Patient information sheet

Not available in web format, please use the contact details below to request a patient information sheet

Condition

Eating attitudes and behaviours

Intervention

In the randomised cross-over study participants will be given iso-energetic, equi-palatable, liquid preloads made from commercially available foods and manipulated according to taste (flavour).

30 participants randomised to
1. Savoury taste
2. Sweet taste
3. Bland taste (control) in counterbalanced order

Intervention type

Other

Phase

Not Applicable

Drug names

Primary outcome measures

1. Food intake at one's pleasure (ad libitum): multi item test meal (buffet)
2. Foods of known macronutrient and energy composition, each item weighed before and after consumption to the nearest 0.1g

Secondary outcome measures

1. Food selection according to taste (savoury or sweet) and fat content (>50% or <25% energy) of items consumed in test meal
2. Subjective appetite (hunger, fullness, prospective consumption) using visisal analogue scales (VAS) score (0 = not at all, 100 = extremely) at 0, +10, +20, +30 minutes following preload consumption
3. Food preferences using computerised task to assess images of foods varying according to taste (savoury or sweet) and fat content (>50% or <25% energy)
4. Liking measured by (VAS) score (0 = not at all, 100 = extremely) at +10 minutes following preload consumption
5. Wanting measured by paired choice reaction time task

Overall trial start date

17/03/2008

Overall trial end date

04/08/2008

Reason abandoned

Eligibility

Participant inclusion criteria

1. Female, in good general health, aged 18-30 years
2. Non-obese (< 30kg/m2)
3. Acceptance of the study foods

Participant type

Patient

Age group

Adult

Gender

Female

Target number of participants

30

Participant exclusion criteria

1. Currently following a weight loss/maintenance routine
2. History of eating or psychological disorders in previous 3 years

Recruitment start date

17/03/2008

Recruitment end date

04/08/2008

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Institute of Psychological Sciences
Leeds
LS2 9JT
United Kingdom

Sponsor information

Organisation

Ajinomoto Co., Inc. (Japan)

Sponsor details

1-1
Suzuki-Cho
Kawasaki-Ku
Kawasaki
210-8681
Japan

Sponsor type

Industry

Website

Funders

Funder type

Research council

Funder name

Ajinomoto Inc. (Japan)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Biotechnology and Biological Sciences Research Council (BBSRC) (UK) (BB/G005524/1)

Alternative name(s)

BBSRC

Funding Body Type

private sector organisation

Funding Body Subtype

other non-profit

Location

United Kingdom

Funder name

European Union (EU) (Belgium) - Seventh Framework Programme (FP7/2007-2013, grant:266408)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2012 results in http://www.ncbi.nlm.nih.gov/pubmed/22131553

Publication citations

Additional files

Editorial Notes

27/11/2015: Publication reference added.