| ISRCTN | ISRCTN74757601 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN74757601 |
| Secondary identifying numbers | V2 |
- Submission date
- 30/04/2013
- Registration date
- 04/07/2013
- Last edited
- 30/07/2015
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Plain English summary of protocol
Background and study aims
Two facts regarding cardiovascular diseases are well established. First, that lowering blood pressure and cholesterol can reduce the risk of heart attacks and strokes to a great extent. Second, about half of all patients prescribed medication discontinue them after about 2 years. This leads to many thousands of avoidable deaths from cardiovascular disease and a significant economic health burden.
An important research question is how adherence to treatment (continuing with prescribed treatment) can be improved in a simple, acceptable and cost-effective way. This study aims to determine the extent to which text message reminders improve adherence to medication.
Who can participate?
Anyone with a mobile phone who has been prescribed cholesterol-lowering or blood pressure lowering treatment for the prevention of cardiovascular disease.
What does the study involve?
Participants are randomly allocated to receiving a programme of text messages or standard care. Participants allocated to text messages receive these for one year. Adherence to the starting medication is assessed after 6 months and after 18 months, using a questionnaire and measurements of blood pressure and blood cholesterol.
What are the possible benefits and risks of participating?
An improvement in medication adherence.
Where is the study run from?
The Wolfson Institute of Preventive Medicine and local London General Practices.
When is the study starting and how long is it expected to run for?
Started in 2012 and lasting until 18 months after the last patient is recruited.
Who is funding the study?
Queen Mary University of London
Who is the main contact?
Dr David Wald
Wolfson Institute of Preventive Medicine, London
Contact information
Scientific
Wolfson Institute of Preventive Medicine
Charterhouse Square
London
EC1M 6BQ
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Other |
| Study type | Treatment |
| Scientific title | INvestigation of TExt message Reminders on Adherence to Cardiac Treatment |
| Study acronym | INTERACT |
| Study objectives | To determine whether programmed text message reminders improve adherence to cardiovascular disease preventive medication. |
| Ethics approval(s) | East London Research Ethics Committee 1, 28/01/2011, ref: 11/H0703/1 |
| Health condition(s) or problem(s) studied | Cardiovascular disease |
| Intervention | Text messages for one year or standard care |
| Intervention type | Other |
| Primary outcome measure | Self-reported adherence assessed after 6 months and after 18 months |
| Secondary outcome measures | 1. Blood pressure 2. Blood cholesterol 3. Health economic analysis |
| Overall study start date | 01/04/2012 |
| Completion date | 01/09/2014 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | 300 |
| Key inclusion criteria | Any patient prescribed a blood pressure or cholesterol lowering medication and who owns a mobile phone. |
| Key exclusion criteria | Does not meet inclusion criteria |
| Date of first enrolment | 01/04/2012 |
| Date of final enrolment | 01/09/2014 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
EC1M 6BQ
United Kingdom
Sponsor information
University/education
Joint R&D Office
5 Walden Street
London
E1 2EF
England
United Kingdom
| gerry.leonard@bartshealth.co.uk | |
| Website | http://www.qmul.ac.uk/ |
"ROR" |
https://ror.org/026zzn846 |
Funders
Funder type
Research organisation
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 05/12/2014 | Yes | No |
