Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
RE03
Study information
Scientific title
Nephrectomy versus no nephrectomy for metastatic renal carcinoma
Acronym
Study hypothesis
To establish whether, in patients with metastatic renal carcinoma, nephrectomy has any advantage.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Condition
Renal Cancer
Intervention
1. One group receives a nephrectomy
2. The other receives no nephrectomy
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
1. Time to progression
2. Metastase rate
3. Quality of life
4. Survival time
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/01/1995
Overall trial end date
01/12/1998
Reason abandoned
Eligibility
Participant inclusion criteria
1. Patient should have locally operable disease and should be fit enough for nephrectomy
2. A renal tumour with clinical or radiological evidence of metastases
3. No previous malignancy (except non-melanotic skin cancer or in situ carcinoma of the cervix)
4. Written informed consent of the patient
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
120
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/01/1995
Recruitment end date
01/12/1998
Locations
Countries of recruitment
United Kingdom
Trial participating centre
MRC Clinical Trials Unit
London
NW1 2DA
United Kingdom
Sponsor information
Organisation
Medical Research Council (MRC) (UK)
Sponsor details
20 Park Crescent
London
W1B 1AL
United Kingdom
+44 (0)20 7636 5422
clinical.trial@headoffice.mrc.ac.uk
Sponsor type
Research council
Website
Funders
Funder type
Research council
Funder name
Medical Research Council (MRC) (UK)
Alternative name(s)
MRC
Funding Body Type
government organisation
Funding Body Subtype
Federal/National Government
Location
United Kingdom
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary