Condition category
Cancer
Date applied
28/02/2001
Date assigned
28/02/2001
Last edited
26/02/2016
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Pat Cook

ORCID ID

Contact details

MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

RE03

Study information

Scientific title

Nephrectomy versus no nephrectomy for metastatic renal carcinoma

Acronym

Study hypothesis

To establish whether, in patients with metastatic renal carcinoma, nephrectomy has any advantage.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Condition

Renal Cancer

Intervention

1. One group receives a nephrectomy
2. The other receives no nephrectomy

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

1. Time to progression
2. Metastase rate
3. Quality of life
4. Survival time

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/01/1995

Overall trial end date

01/12/1998

Reason abandoned

Eligibility

Participant inclusion criteria

1. Patient should have locally operable disease and should be fit enough for nephrectomy
2. A renal tumour with clinical or radiological evidence of metastases
3. No previous malignancy (except non-melanotic skin cancer or in situ carcinoma of the cervix)
4. Written informed consent of the patient

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

120

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

01/01/1995

Recruitment end date

01/12/1998

Locations

Countries of recruitment

United Kingdom

Trial participating centre

MRC Clinical Trials Unit
London
NW1 2DA
United Kingdom

Sponsor information

Organisation

Medical Research Council (MRC) (UK)

Sponsor details

20 Park Crescent
London
W1B 1AL
United Kingdom
+44 20 7636 5422
clinical.trial@headoffice.mrc.ac.uk

Sponsor type

Research council

Website

http://www.mrc.ac.uk

Funders

Funder type

Research council

Funder name

Medical Research Council (MRC) (UK)

Alternative name(s)

MRC

Funding Body Type

private sector organisation

Funding Body Subtype

other non-profit

Location

United Kingdom

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes

26/02/2016: No publications found, study status unverified.