Nephrectomy versus no nephrectomy for metastatic renal carcinoma

ISRCTN	ISRCTN75184582
DOI	https://doi.org/10.1186/ISRCTN75184582
Secondary identifying numbers	RE03

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Dr Pat Cook
Scientific

MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Treatment
Scientific title	Nephrectomy versus no nephrectomy for metastatic renal carcinoma
Study objectives	To establish whether, in patients with metastatic renal carcinoma, nephrectomy has any advantage.
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Renal Cancer
Intervention	1. One group receives a nephrectomy 2. The other receives no nephrectomy
Intervention type	Other
Primary outcome measure	1. Time to progression 2. Metastase rate 3. Quality of life 4. Survival time
Secondary outcome measures	Not provided at time of registration
Overall study start date	01/01/1995
Completion date	01/12/1998

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target number of participants	120
Key inclusion criteria	1. Patient should have locally operable disease and should be fit enough for nephrectomy 2. A renal tumour with clinical or radiological evidence of metastases 3. No previous malignancy (except non-melanotic skin cancer or in situ carcinoma of the cervix) 4. Written informed consent of the patient
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	01/01/1995
Date of final enrolment	01/12/1998

MRC Clinical Trials Unit

London
NW1 2DA
United Kingdom

Medical Research Council (MRC) (UK)
Research council

20 Park Crescent
London
W1B 1AL
United Kingdom

Phone	+44 (0)20 7636 5422
Email	clinical.trial@headoffice.mrc.ac.uk
Website	http://www.mrc.ac.uk

Research council

Medical Research Council (MRC) (UK)
Government organisation / National government

Alternative name(s): Medical Research Council (United Kingdom), UK Medical Research Council, MRC
Location: United Kingdom

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

26/02/2016: No publications found, study status unverified.