Plain English Summary
Background and study aims
The humerus is the long bone that connects the shoulder to the elbow. When it is fractured, it is usually fixed using a less invasive surgical procedure called deltoid muscle splitting. However, this procedure has concerns about its effectiveness in aging people and complex fractures. The efficacy of the using a ‘locking plate’ needs to be evaluated using the anterolateral (located in front and to one side) deltoid splitting approach and specially examine the effect depending on the patient’s age, gender and fracture type. The aim of this study is to evaluate the efficacy of a humeral locking plate using the anterolateral deltoid splitting approach and to specifically examine the effect of patient age, gender and fracture pattern on surgical outcomes.
Who can participate?
Adults aged 36 to 77 years old who have humerus fractures.
What does the study involve?
This is a case review study of proximal humerus fractures that are treated surgically with the Locking compression plate from 2009 to 2011.The researchers gathered data about the surgery, reviewed record and radiographs, as well as gender, age, fracture type and their follow up. This is done to assess the surgical outcomes to this procedure.
What are the possible benefits and risks of participating?
There are no benefits or risks with participating.
Where is the study run from?
Chang Gung Memorial Hospital (Taiwan)
When is the study starting and how long is it expected to run for?
December 2008 to June 2017
Who is funding the study?
Chang Gung Medical Foundation (Taiwan)
Who is the main contact?
Dr Alvin Chao-Yu Chen
Influence of age, gender, and radiographic features on the deltoid splitting approach for surgical osteosynthesis in displaced proximal humerus fractures
Examining the influence of the surgical approach for management of displaced proximal humerus fractures and to specifically examine the impact of patient age and fracture pattern on the outcomes.
Institutional Review Board of Chang Gung Memorial Hospital, 07/06/2017, ref: No. 201700826B0
Observational case-control study
Primary study design
Secondary study design
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Examining the influence of patient demographics on the influence of surgical approach in displaced proximal humerus fractures
This study retrospectively evaluated cases of unilateral proximal humerus fractures that were treated surgically with the Locking Compression Plate (LCP), as per the Neer classification criteria at our institute between 2009 and 2011.
Institutional review board approval was obtained to perform a review of patients’ records and radiographs; informed consent was obtained from 132 patients with displaced proximal humerus fractures. All these cases of proximal humerus fractures either met the indications for operative treatment outlined by Neer or were considered unstable when tested for passive motion with an image intensifier.
Those with pathological fractures, head split fractures, open fractures, fractures with primary neurovascular damage, multiple fractures, and cases lost to follow-up are excluded from the study. Forty-two patients, who underwent anterolateral deltoid splitting surgery, are selected for a retrospective matched pairs analysis according to their age (younger than 60 years vs. older than 60 years), gender, and fracture type with a minimum follow-up of 24 months.
Primary outcome measures
Fracture healing is measured using the data from the cases.
Secondary outcome measures
1. Functional outcomes are measured using the data from the cases
2. Radio is measured using the data from the cases
Overall trial start date
Overall trial end date
Participant inclusion criteria
1. Displaced proximal humerus fractures. All these cases of proximal humerus fractures either met the indications for operative treatment outlined by Neer or were considered unstable when tested for passive motion with an image intensifier.
2. Aged 36 to 77 years old
Target number of participants
Participant exclusion criteria
1. Patients with pathological fractures
2. Head split fractures
3. Open fractures
4. Fractures with primary neurovascular damage
5. Multiple fractures
6. Cases lost to follow-up were excluded from the study
Recruitment start date
Recruitment end date
Countries of recruitment
Trial participating centre
Chang Gung Memorial Hospital
5th Fu-Hsin Street Kweishan District
Chang Gung Medical Foundation
Funding Body Type
Funding Body Subtype
Results and Publications
Publication and dissemination plan
Plans to publish our reports in peer-reviewed journals this year.
IPD sharing statement:
The datasets generated during and/or analysed during the current study are/will be available upon request from Alvin Chao-Yu Chen, MD at email@example.com
Intention to publish date
Participant level data
Available on request
Results - basic reporting