Condition category
Skin and Connective Tissue Diseases
Date applied
30/09/2004
Date assigned
30/09/2004
Last edited
27/09/2011
Prospective/Retrospective
Retrospectively registered
Overall trial status
Stopped
Recruitment status
Stopped

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Miss Julie C Day

ORCID ID

Contact details

Podiatry Department
First Floor East Wing
St Pancras Hospital
4 St Pancras Way
London
NW1 0PE
United Kingdom
+44 (0)20 7530 3871
jules.day@virgin.net

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0530132857

Study information

Scientific title

Acronym

Study hypothesis

Verrucae, or warts, are a common, infectious and sometimes painful problem, but it is uncertain which is the most effective treatment. We plan to compare two commonly used treatments for warts: salicylic acid with monochloracetic acid or cryotherapy. We are interested to know how effective the two treatments are in cleaning up the warts and also how cost effective the two treatments are compared to one another. Patients will also be asked about acceptability with their treatment and possible side effects such as pain.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Skin and Connective Tissue Diseases: Warts

Intervention

Database analysis, Questionnaires, Randomised Controlled Trial - to compare:
1. Cryotherapy
2. Salicylic acid with monochloracetic acid
For treatment of plantar warts

August 2008: Trial stopped 2006.

Intervention type

Drug

Phase

Not Specified

Drug names

Salicylic Acid with Monochloracetic Acid

Primary outcome measures

A recent systematic review has highlighted the uncertainty with respect to the optimal treatment of verrucae and warts (Gibbs Set et al, BMJ, 2002). Freezing warts using cryotherapy is widespread but there is little evidence showing it is effective. However, it may be relatively cost effective compared with chemical treatments in that fewer visits may be required to eradicate the condition. There is a need for a randomised controlled trial with a cost effectiveness analysis to ascertain which is the best approach. The evidence base would aid clinical decision makers and also health care managers in resource allocation

Secondary outcome measures

Not provided at time of registration

Overall trial start date

29/10/2003

Overall trial end date

31/08/2004

Reason abandoned

Problems with staffing.

Eligibility

Participant inclusion criteria

Not provided at time of registration

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

133 in each treatment group

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

29/10/2003

Recruitment end date

31/08/2004

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Podiatry Department
London
NW1 0PE
United Kingdom

Sponsor information

Organisation

Department of Health

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Sponsor type

Government

Website

http://www.dh.gov.uk/Home/fs/en

Funders

Funder type

Research organisation

Funder name

North Central London Research Consortium (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes