Contact information
Type
Scientific
Primary contact
Miss Julie C Day
ORCID ID
Contact details
Podiatry Department
First Floor East Wing
St Pancras Hospital
4 St Pancras Way
London
NW1 0PE
United Kingdom
+44 (0)20 7530 3871
jules.day@virgin.net
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0530132857
Study information
Scientific title
Acronym
Study hypothesis
Verrucae, or warts, are a common, infectious and sometimes painful problem, but it is uncertain which is the most effective treatment. We plan to compare two commonly used treatments for warts: salicylic acid with monochloracetic acid or cryotherapy. We are interested to know how effective the two treatments are in cleaning up the warts and also how cost effective the two treatments are compared to one another. Patients will also be asked about acceptability with their treatment and possible side effects such as pain.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Skin and Connective Tissue Diseases: Warts
Intervention
Database analysis, Questionnaires, Randomised Controlled Trial - to compare:
1. Cryotherapy
2. Salicylic acid with monochloracetic acid
For treatment of plantar warts
August 2008: Trial stopped 2006.
Intervention type
Drug
Phase
Not Specified
Drug names
Salicylic Acid with Monochloracetic Acid
Primary outcome measure
A recent systematic review has highlighted the uncertainty with respect to the optimal treatment of verrucae and warts (Gibbs Set et al, BMJ, 2002). Freezing warts using cryotherapy is widespread but there is little evidence showing it is effective. However, it may be relatively cost effective compared with chemical treatments in that fewer visits may be required to eradicate the condition. There is a need for a randomised controlled trial with a cost effectiveness analysis to ascertain which is the best approach. The evidence base would aid clinical decision makers and also health care managers in resource allocation
Secondary outcome measures
Not provided at time of registration
Overall trial start date
29/10/2003
Overall trial end date
31/08/2004
Reason abandoned (if study stopped)
Problems with staffing.
Eligibility
Participant inclusion criteria
Not provided at time of registration
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
133 in each treatment group
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
29/10/2003
Recruitment end date
31/08/2004
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Podiatry Department
London
NW1 0PE
United Kingdom
Sponsor information
Organisation
Department of Health
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Research organisation
Funder name
North Central London Research Consortium (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list