Condition category
Nutritional, Metabolic, Endocrine
Date applied
18/05/2001
Date assigned
18/05/2001
Last edited
04/10/2018
Prospective/Retrospective
Prospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr John Newsom-Davis

ORCID ID

Contact details

Department of Clinical Neurology
University of Oxford
Radcliffe Infirmary
Oxford
OX2 6HE
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

G0100023

Study information

Scientific title

Thymectomy trial in non-thymomatous myasthenia gravis patients receiving immunosuppressive therapy

Acronym

TxMG trial

Study hypothesis

To determine whether extended trans-sternal thymectomy reduces corticosteroid requirements for patients with generalised acetylcholine receptor (AChR) antibody-positive non-thymomatous myasthenia gravis (MG).

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Not available in web format, please use the contact details to request a patient information sheet

Condition

Endocrinology

Intervention

Not provided at time of registration

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measure

Not provided at time of registration

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/06/2005

Overall trial end date

01/06/2007

Reason abandoned (if study stopped)

Eligibility

Participant inclusion criteria

Not provided at time of registration

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

Not provided at time of registration

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

01/06/2005

Recruitment end date

01/06/2007

Locations

Countries of recruitment

United Kingdom

Trial participating centre

University of Oxford
Oxford
OX2 6HE
United Kingdom

Sponsor information

Organisation

Sponsor not defined - application in progress

Sponsor details

-
-
-
United Kingdom

Sponsor type

Not defined

Website

Funders

Funder type

Not defined

Funder name

Not provided at time of registration

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Basic results (scientific)

Publication list

2008 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/18567886
2016 results in: http://www.ncbi.nlm.nih.gov/pubmed/27509100

Publication citations

  1. Protocol

    Newsom-Davis J, Cutter G, Wolfe GI, Kaminski HJ, Jaretzki A, Minisman G, Aban I, Conwit R, Status of the thymectomy trial for nonthymomatous myasthenia gravis patients receiving prednisone., Ann. N. Y. Acad. Sci., 2008, 1132, 344-347, doi: 10.1196/annals.1405.014.

Additional files

Editorial Notes

04/10/2018: Publication reference added.