Contact information
Type
Scientific
Primary contact
Dr Michael Tunney
ORCID ID
Contact details
Queen's University Belfast
School of Pharmacy
Medical Biology Centre
97 Lisburn Road
Belfast
BT9 7BL
United Kingdom
m.tunney@qub.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
EAT/2953/04
Study information
Scientific title
Acronym
Study hypothesis
1. What is the prevalence of MRSA in nursing homes in the Northern Health and Social Services Board?
2. Can an improvement in infection control standards result in a decrease in MRSA prevalence in nursing homes in this board area?
Ethics approval
Ethical approval granted by the Office for Research Ethics Committees Northern Ireland (ORECNI) on 03/11/2005, reference number: 05/NIR03/154
Study design
Phase 1 is observational; Phase 2 is a cluster randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Prevention
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Condition
Methicillin-resistant Staphyloccus aureus (MRSA) colonisation
Intervention
Nasal and skin swab and urinary catheter sample where appropriate from residents in both phases 1 and 2. In phase 2, homes assigned to the intervention group will receive an audit of current infection control practices followed by infection control training and feedback. In control homes, routine care will continue as normal.
Intervention type
Other
Phase
Phase I/II
Drug names
Primary outcome measure
In phase 1, determination of MRSA prevalence in nursing homes in Northern Health and Social Services (NHSSB). In phase 2, the prevalence of MRSA in intervention homes compared to control homes following infection control intervention, audit and feedback.
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/11/2005
Overall trial end date
01/11/2008
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Phase 1: all nursing homes in the Northern Board will be asked to participate. Within these homes, all residents and staff will be invited to participate.
Phase 2: For a nursing home to be considered in this phase, it must have at least 20 consenting adults.
Participant type
Patient
Age group
Senior
Gender
Both
Target number of participants
All 66 nursing homes in NHSSB
Participant exclusion criteria
Nursing home residents who are terminally ill, in a coma or not deemed fit to personally give consent and have no next-of-kin available to give consent, will be excluded from both phases of the trial. For staff, there are no specific exclusion criteria, other than failure to provide written informed consent.
Recruitment start date
01/11/2005
Recruitment end date
01/11/2008
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Queen's University Belfast
Belfast
BT9 7BL
United Kingdom
Sponsor information
Organisation
Queens University Belfast (UK)
Sponsor details
Lanyon Building
University Road
Belfast
BT7 1NN
United Kingdom
+44 (0) 289 027 2568
d.weir@qub.ac.uk
Sponsor type
University/education
Website
Funders
Funder type
Government
Funder name
Central Services Agency, a part of the Northern Ireland Health and Social Services (NIHSS), Reasearch and Development Office (EAT/2953/04)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
1. 2010 results in http://www.ncbi.nlm.nih.gov/pubmed/20451294
Publication citations
-
Results
Baldwin NS, Gilpin DF, Tunney MM, Kearney MP, Crymble L, Cardwell C, Hughes CM, Cluster randomised controlled trial of an infection control education and training intervention programme focusing on meticillin-resistant Staphylococcus aureus in nursing homes for older people., J. Hosp. Infect., 2010, 76, 1, 36-41, doi: 10.1016/j.jhin.2010.03.006.