Condition category
Infections and Infestations
Date applied
06/06/2006
Date assigned
19/06/2006
Last edited
04/01/2012
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Michael Tunney

ORCID ID

Contact details

Queen's University Belfast
School of Pharmacy
Medical Biology Centre
97 Lisburn Road
Belfast
BT9 7BL
United Kingdom
m.tunney@qub.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

EAT/2953/04

Study information

Scientific title

Acronym

Study hypothesis

1. What is the prevalence of MRSA in nursing homes in the Northern Health and Social Services Board?
2. Can an improvement in infection control standards result in a decrease in MRSA prevalence in nursing homes in this board area?

Ethics approval

Ethical approval granted by the Office for Research Ethics Committees Northern Ireland (ORECNI) on 03/11/2005, reference number: 05/NIR03/154

Study design

Phase 1 is observational; Phase 2 is a cluster randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Prevention

Patient information sheet

Not available in web format, please use the contact details below to request a patient information sheet

Condition

Methicillin-resistant Staphyloccus aureus (MRSA) colonisation

Intervention

Nasal and skin swab and urinary catheter sample where appropriate from residents in both phases 1 and 2. In phase 2, homes assigned to the intervention group will receive an audit of current infection control practices followed by infection control training and feedback. In control homes, routine care will continue as normal.

Intervention type

Other

Phase

Phase I/II

Drug names

Primary outcome measures

In phase 1, determination of MRSA prevalence in nursing homes in Northern Health and Social Services (NHSSB). In phase 2, the prevalence of MRSA in intervention homes compared to control homes following infection control intervention, audit and feedback.

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/11/2005

Overall trial end date

01/11/2008

Reason abandoned

Eligibility

Participant inclusion criteria

Phase 1: all nursing homes in the Northern Board will be asked to participate. Within these homes, all residents and staff will be invited to participate.
Phase 2: For a nursing home to be considered in this phase, it must have at least 20 consenting adults.

Participant type

Patient

Age group

Senior

Gender

Both

Target number of participants

All 66 nursing homes in NHSSB

Participant exclusion criteria

Nursing home residents who are terminally ill, in a coma or not deemed fit to personally give consent and have no next-of-kin available to give consent, will be excluded from both phases of the trial. For staff, there are no specific exclusion criteria, other than failure to provide written informed consent.

Recruitment start date

01/11/2005

Recruitment end date

01/11/2008

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Queen's University Belfast
Belfast
BT9 7BL
United Kingdom

Sponsor information

Organisation

Queens University Belfast (UK)

Sponsor details

Lanyon Building
University Road
Belfast
BT7 1NN
United Kingdom
+44 (0) 289 027 2568
d.weir@qub.ac.uk

Sponsor type

University/education

Website

Funders

Funder type

Government

Funder name

Central Services Agency, a part of the Northern Ireland Health and Social Services (NIHSS), Reasearch and Development Office (EAT/2953/04)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

1. 2010 results in http://www.ncbi.nlm.nih.gov/pubmed/20451294

Publication citations

  1. Results

    Baldwin NS, Gilpin DF, Tunney MM, Kearney MP, Crymble L, Cardwell C, Hughes CM, Cluster randomised controlled trial of an infection control education and training intervention programme focusing on meticillin-resistant Staphylococcus aureus in nursing homes for older people., J. Hosp. Infect., 2010, 76, 1, 36-41, doi: 10.1016/j.jhin.2010.03.006.

Additional files

Editorial Notes