Bolus thrombolysis in cardiac arrest: a randomised controlled trial
| ISRCTN | ISRCTN81334888 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN81334888 |
| Secondary identifying numbers | N0280113809 |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 31/08/2010
- Recruitment status
- Stopped
- Overall study status
- Stopped
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Jane McVicar
Scientific
Scientific
A&E
Arrowe Park Hospital
Arrowe Park Road
Upton
Wirral
CH49 5PE
United Kingdom
| Phone | +44 (0)151 230 0640 |
|---|---|
| beluga.whale@btopenworld.com |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | |
| Study objectives | Does bolus thrombolysis improve survival? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Cardiovascular: Bolus thrombolysis |
| Intervention | Single bolus dose tenecteplase or placebo given after first iv adrenaline on arrival in Accident and Emergency. Questionnaire to be completed by staff and collected by researcher. Added 30/08/10: trials was discontinued as of June 2006 |
| Intervention type | Other |
| Primary outcome measure | Survival (numbers), adverse events/bleeding, neurological status of survivors. |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/09/2002 |
| Completion date | 30/09/2005 |
| Reason abandoned (if study stopped) | Lack of funding/sponsorship |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | Not provided at time of registration |
| Key inclusion criteria | 1. All patients attending Accident and Emergency with out-of-hospital cardiac arrest 2. Aged 16-79 years old |
| Key exclusion criteria | 1. Inappropriate for resuscitation 2. Late pregnancy |
| Date of first enrolment | 01/09/2002 |
| Date of final enrolment | 30/09/2005 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
A&E
Wirral
CH49 5PE
United Kingdom
CH49 5PE
United Kingdom
Sponsor information
Department of Health (UK)
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.doh.gov.uk |
|---|
Funders
Funder type
Government
Wirral Hospitals NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
