Condition category
Circulatory System
Date applied
12/09/2003
Date assigned
12/09/2003
Last edited
31/08/2010
Prospective/Retrospective
Retrospectively registered
Overall trial status
Stopped
Recruitment status
Stopped

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Jane McVicar

ORCID ID

Contact details

A&E
Arrowe Park Hospital
Arrowe Park Road
Upton
Wirral
CH49 5PE
United Kingdom
+44 (0)151 230 0640
beluga.whale@btopenworld.com

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0280113809

Study information

Scientific title

Acronym

Study hypothesis

Does bolus thrombolysis improve survival?

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Cardiovascular: Bolus thrombolysis

Intervention

Single bolus dose tenecteplase or placebo given after first iv adrenaline on arrival in Accident and Emergency. Questionnaire to be completed by staff and collected by researcher.

Added 30/08/10: trials was discontinued as of June 2006

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Survival (numbers), adverse events/bleeding, neurological status of survivors.

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/09/2002

Overall trial end date

30/09/2005

Reason abandoned

Lack of funding/sponsorship

Eligibility

Participant inclusion criteria

1. All patients attending Accident and Emergency with out-of-hospital cardiac arrest
2. Aged 16-79 years old

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

Not provided at time of registration

Participant exclusion criteria

1. Inappropriate for resuscitation
2. Late pregnancy

Recruitment start date

01/09/2002

Recruitment end date

30/09/2005

Locations

Countries of recruitment

United Kingdom

Trial participating centre

A&E
Wirral
CH49 5PE
United Kingdom

Sponsor information

Organisation

Department of Health (UK)

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Sponsor type

Government

Website

http://www.doh.gov.uk

Funders

Funder type

Government

Funder name

Wirral Hospitals NHS Trust (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes