Contact information
Type
Scientific
Primary contact
Dr Jane McVicar
ORCID ID
Contact details
A&E
Arrowe Park Hospital
Arrowe Park Road
Upton
Wirral
CH49 5PE
United Kingdom
+44 (0)151 230 0640
beluga.whale@btopenworld.com
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0280113809
Study information
Scientific title
Acronym
Study hypothesis
Does bolus thrombolysis improve survival?
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Cardiovascular: Bolus thrombolysis
Intervention
Single bolus dose tenecteplase or placebo given after first iv adrenaline on arrival in Accident and Emergency. Questionnaire to be completed by staff and collected by researcher.
Added 30/08/10: trials was discontinued as of June 2006
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measure
Survival (numbers), adverse events/bleeding, neurological status of survivors.
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/09/2002
Overall trial end date
30/09/2005
Reason abandoned (if study stopped)
Lack of funding/sponsorship
Eligibility
Participant inclusion criteria
1. All patients attending Accident and Emergency with out-of-hospital cardiac arrest
2. Aged 16-79 years old
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
Not provided at time of registration
Participant exclusion criteria
1. Inappropriate for resuscitation
2. Late pregnancy
Recruitment start date
01/09/2002
Recruitment end date
30/09/2005
Locations
Countries of recruitment
United Kingdom
Trial participating centre
A&E
Wirral
CH49 5PE
United Kingdom
Sponsor information
Organisation
Department of Health (UK)
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
Wirral Hospitals NHS Trust (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list