Condition category
Circulatory System
Date applied
04/02/2002
Date assigned
04/02/2002
Last edited
08/10/2013
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Munther Khamashta

ORCID ID

Contact details

Louise Coote Lupus Unit
St Thomas' s Hospital
The Rayne Institute
London
SE1 7EH
United Kingdom
+44 (0)20 7928 9292
106404.2325@compuserve.com

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

K0554

Study information

Scientific title

Acronym

ALIAPAS

Study hypothesis

Not provided at time of registration

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Condition

Prevention of thrombosis

Intervention

Patients will be randomised to either low dose (75 mg) aspirin or low-dose aspirin and low international normalised ratio (INR) warfarin

Intervention type

Drug

Phase

Not Specified

Drug names

Aspirin, warfarin

Primary outcome measures

Not provided at time of registration

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/09/2000

Overall trial end date

01/01/2006

Reason abandoned

Eligibility

Participant inclusion criteria

Patients positive for antiphospholipid antibodies

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

Not provided at time of registration

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

01/09/2000

Recruitment end date

01/01/2006

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Louise Coote Lupus Unit
London
SE1 7EH
United Kingdom

Sponsor information

Organisation

Arthritis Research Campaign (ARC) (UK)

Sponsor details

Copeman House
St Mary's Court
St Mary's Gate
Chesterfield
Derbyshire
S41 7TD
United Kingdom
-
info@arc.org.uk

Sponsor type

Charity

Website

http://www.arc.org.uk

Funders

Funder type

Charity

Funder name

Arthritis Research Campaign (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2013 results in: http://www.ncbi.nlm.nih.gov/pubmed/24097288

Publication citations

  1. Results

    Cuadrado MJ, Bertolaccini ML, Seed PT, Tektonidou MG, Aguirre A, Mico L, Gordon C, Ruiz-Irastorza G, Egurbide MV, Gil A, Espinosa G, Houssiau F, Rahman A, Martin H, McHugh N, Galindo M, Akil M, Amigo MC, Murru V, Khamashta MA, Low-dose aspirin vs low-dose aspirin plus low-intensity warfarin in thromboprophylaxis: a prospective, multicentre, randomized, open, controlled trial in patients positive for antiphospholipid antibodies (ALIWAPAS)., Rheumatology (Oxford), 2014, 53, 2, 275-284, doi: 10.1093/rheumatology/ket313.

Additional files

Editorial Notes