Central line insertion project (CLIP)
ISRCTN | ISRCTN85787933 |
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DOI | https://doi.org/10.1186/ISRCTN85787933 |
Secondary identifying numbers | HTA 95/16/06 |
- Submission date
- 25/04/2003
- Registration date
- 25/04/2003
- Last edited
- 08/11/2022
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Other
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Ms Angela Boland
Scientific
Scientific
University of Liverpool
Ashton Street Medical School
Ashton Street
Liverpool
L69 3GE
United Kingdom
Phone | +44 (0)151 794 5541 |
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a.boland@liv.ac.uk |
Study information
Study design | Randomised controlled trial |
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Primary study design | Interventional |
Secondary study design | Randomised controlled trial |
Study setting(s) | Not specified |
Study type | Not Specified |
Scientific title | Central line insertion project (CLIP) |
Study acronym | CLIP |
Study objectives | A single centre randomised trial of central venous catheter insertion by a clinical nurse specialist, under image guidance or on the ward without routine access to image guidance. Approximately 400 patients will be randomised to compare safety, adverse events, efficacy, quality of life and cost. The study will identify the incremental cost effectiveness ratio for nurse insertion and develop and evaluate a training programme to generalise these benefits throughout the NHS. A model will be developed to analyse the long term benefits for patients and the NHS from generalised adoption of the optimal methods of insertion throughout the NHS. |
Ethics approval(s) | Not provided at time of registration. |
Health condition(s) or problem(s) studied | Not applicable |
Intervention | 1. Central venous catheter insertion by a clinical nurse specialist under image guidance 2. Central venous catheter insertion on the ward without routine access to image guidance |
Intervention type | Other |
Primary outcome measure | Catheter-tip misplacement and this was expected to be higher in the blind arm. When comparing the skill level of the trainer and the trainees, pneumothorax was the primary clinical outcome measure. |
Secondary outcome measures | Other outcomes measures included arterial puncture, haematoma, infection, failed insertion and assistance from other healthcare professionals. |
Overall study start date | 01/01/1999 |
Completion date | 31/12/2000 |
Eligibility
Participant type(s) | Patient |
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Age group | Adult |
Sex | Both |
Target number of participants | 400 |
Key inclusion criteria | Not provided at time of registration. |
Key exclusion criteria | Not provided at time of registration. |
Date of first enrolment | 01/01/1999 |
Date of final enrolment | 31/12/2000 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
University of Liverpool
Liverpool
L69 3GE
United Kingdom
L69 3GE
United Kingdom
Sponsor information
Department of Health (UK)
Government
Government
Quarry House
Quarry Hill
Leeds
LS2 7UE
United Kingdom
Phone | +44 (0)1132 545 843 |
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Sheila.Greener@doh.gsi.gov.uk | |
Website | http://www.dh.gov.uk/en/index.htm |
https://ror.org/03sbpja79 |
Funders
Funder type
Government
NIHR Health Technology Assessment Programme - HTA (UK)
No information available
Results and Publications
Intention to publish date | |
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Individual participant data (IPD) Intention to share | No |
IPD sharing plan summary | Not provided at time of registration |
Publication and dissemination plan | Not provided at time of registration |
IPD sharing plan | Not provided at time of registration |
Study outputs
Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
---|---|---|---|---|---|
Results article | HTA monograph | 01/04/2003 | Yes | No |
Editorial Notes
08/11/2022: Internal review.