Condition category
Signs and Symptoms
Date applied
12/09/2003
Date assigned
12/09/2003
Last edited
20/10/2011
Prospective/Retrospective
Retrospectively registered
Overall trial status
Stopped
Recruitment status
Stopped

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Dominic Aldington

ORCID ID

Contact details

Pain Relief Unit
The Churchill Hospital
Old Road
Headington
Oxford
OX3 7LJ
United Kingdom
+44 01865 226193
daldington@mac.com

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0176113615

Study information

Scientific title

Acronym

Study hypothesis

Adenosine is used as an analgesic in certain circumstances and it is possible that given as a Bier's block it will relieve pain. Previous unpublished neurophysiological studies in healthy volunteers have shown that it relieves pain of the tourniquet. It is planned to investigate the effect of adenosine as a Bier's block on peripheral neuopathic pain and also to confirm or deny this effect on tourniquet pain.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Signs and Symptoms: Pain

Intervention

Adenosine vs placebo

Added 18 July 2008: trial stopped

Intervention type

Drug

Phase

Not Specified

Drug names

adenosine

Primary outcome measures

1. Pain intensities and relief, both before and for 1 month after each injection. In addition all side effects will be documented and at the end of the study patient satisfaction with each injection.
2. Pain intensity from the tourniquet during each injection

Secondary outcome measures

Not provided at time of registration

Overall trial start date

10/05/2002

Overall trial end date

31/12/2002

Reason abandoned

Insufficient data

Eligibility

Participant inclusion criteria

Not provided at time of registration

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

30 patients

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

10/05/2002

Recruitment end date

31/12/2002

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Pain Relief Unit
Oxford
OX3 7LJ
United Kingdom

Sponsor information

Organisation

Department of Health (UK)

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Sponsor type

Government

Website

http://www.doh.gov.uk

Funders

Funder type

Government

Funder name

Oxford Radcliffe Hospitals NHS Trust (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes