Contact information
Type
Scientific
Primary contact
Dr Dominic Aldington
ORCID ID
Contact details
Pain Relief Unit
The Churchill Hospital
Old Road
Headington
Oxford
OX3 7LJ
United Kingdom
+44 01865 226193
daldington@mac.com
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0176113615
Study information
Scientific title
Acronym
Study hypothesis
Adenosine is used as an analgesic in certain circumstances and it is possible that given as a Bier's block it will relieve pain. Previous unpublished neurophysiological studies in healthy volunteers have shown that it relieves pain of the tourniquet. It is planned to investigate the effect of adenosine as a Bier's block on peripheral neuopathic pain and also to confirm or deny this effect on tourniquet pain.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Signs and Symptoms: Pain
Intervention
Adenosine vs placebo
Added 18 July 2008: trial stopped
Intervention type
Drug
Phase
Not Specified
Drug names
adenosine
Primary outcome measures
1. Pain intensities and relief, both before and for 1 month after each injection. In addition all side effects will be documented and at the end of the study patient satisfaction with each injection.
2. Pain intensity from the tourniquet during each injection
Secondary outcome measures
Not provided at time of registration
Overall trial start date
10/05/2002
Overall trial end date
31/12/2002
Reason abandoned
Insufficient data
Eligibility
Participant inclusion criteria
Not provided at time of registration
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
30 patients
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
10/05/2002
Recruitment end date
31/12/2002
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Pain Relief Unit
Oxford
OX3 7LJ
United Kingdom
Sponsor information
Organisation
Department of Health (UK)
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
Oxford Radcliffe Hospitals NHS Trust (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary